Muscle MRI findings of X-linked spinal and bulbar muscular atrophy

Journal of the Neurological Sciences
Tadanori HamanoMasaru Kuriyama

Abstract

We report here muscle MRI findings of the lower limb in X-linked spinal and bulbar muscular atrophy (SBMA). T1-weighted imaging of muscle MRI disclosed that the thigh muscles, including the semimembranosus, biceps femoris longus and the vastus lateralis muscles, showed high intensity signals with atrophy. Contrarily, the sartorius, gracilis and rectus femoris muscles were comparably preserved. Not only the thigh muscles, but also the calf muscles including the gastrocnemius medialis and lateralis, and soleus muscles showed high intensity signals. In amyotrophic lateral sclerosis (ALS), the leg muscles are generally atrophic, but the selective pattern of fatty degeneration, seen in SBMA was not observed. Muscle MRI is a useful method of estimating the distribution and severity of SBMA in affected muscles.

References

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Citations

May 1, 2009·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·J Finsterer
Apr 27, 2011·Okajimas Folia Anatomica Japonica·Keisuke InaYoshihisa Fujikura
Sep 18, 2010·Journal of the Neurological Sciences·J Finsterer
Aug 10, 2010·Biochemical and Biophysical Research Communications·Yoshiaki ItoigawaEiji Itoi
Jun 4, 2005·Acta Neurologica Scandinavica·Jae-Hyeok LeeDae-Seong Kim
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May 10, 2007·Molecular and Cellular Biochemistry·Akira Wagatsuma
Oct 27, 2018·Frontiers in Neurology·Giorgia QuerinPierre-Francois Pradat
Mar 20, 2019·Scientific Reports·Julia R DahlqvistJohn Vissing
Jun 22, 2021·Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration·Alexander Kriss, Thomas Jenkins

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