Muscle pain: sensory implications and interaction with motor control

The Clinical Journal of Pain
Lars Arendt-Nielsen, T Graven-Nielsen

Abstract

Muscle hyperalgesia and referred pain plays an important role in chronic musculoskeletal pain. New knowledge on the involved basic mechanisms and better methods to assess muscle pain in the clinic are needed to revise and optimize the treatment regimes. Increased muscle sensitivity is manifested as (1) pain evoked by a normally non-nociceptive stimulus (allodynia), (2) increased pain intensity evoked by nociceptive stimuli (hyperalgesia), or (3) increased referred pain areas with associated somatosensory changes. Quantitative sensory testing provides the possibility to evaluate these manifestations in a standardized way in patients suffering from musculoskeletal pain or in healthy volunteers. Some manifestations of sensitisation, such as expanded referred muscle pain areas in chronic musculoskeletal pain patients, can be explained from animal experiments showing extrasegmental spread of sensitisation. An important part of the pain manifestations (eg, tenderness and referred pain) related to chronic musculoskeletal disorders may be due to peripheral and central sensitization, which play a role in the transition from acute to chronic pain. In recent years, it has become evident that muscle pain can interfere with motor control st...Continue Reading

References

Apr 1, 1995·The Journal of Physiology·C JamesD A Jones
Aug 1, 1993·Scandinavian Journal of Work, Environment & Health·K B VeierstedP Andersen
Apr 1, 1997·Electroencephalography and Clinical Neurophysiology·T Graven-NielsenL Arendt-Nielsen
Feb 24, 1999·European Journal of Applied Physiology and Occupational Physiology·P MadeleineL Arendt-Nielsen
Nov 7, 2000·British Journal of Anaesthesia·M CuratoloL Arendt-Nielsen
Jun 19, 2001·Medicine and Science in Sports and Exercise·P J O'Connor, D B Cook
Feb 20, 2003·International Archives of Occupational and Environmental Health·Pascal MadeleineLars Arendt-Nielsen
Aug 30, 2003·Current Pain and Headache Reports·Lars Arendt-Nielsen, Thomas Graven-Nielsen
Nov 14, 2003·Journal of Neurophysiology·Dario FarinaThomas Graven-Nielsen
Nov 19, 2003·The Journal of Pain : Official Journal of the American Pain Society·Romanas PolianskisLars Arendt-Nielsen
Dec 20, 2003·European Journal of Applied Physiology·Andrei CiubotariuThomas Graven-Nielsen
Mar 27, 2004·European Journal of Applied Physiology·Ulysses Fernandes ErvilhaThomas Graven-Nielsen
May 26, 2004·Pain·Margaret A Caudill-SlosbergSteven Woloshin
Oct 14, 2004·Experimental Brain Research·Thomas Graven-NielsenLars Arendt-Nielsen
Jun 10, 2005·The Journal of Pain : Official Journal of the American Pain Society·Hongling NieThomas Graven-Nielsen
Sep 1, 1995·Journal of Electromyography and Kinesiology : Official Journal of the International Society of Electrophysiological Kinesiology·P Svensson, L Arendt-Nielsen

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Citations

Apr 24, 2010·Journal of Occupational Rehabilitation·Judith E GoldJudith K Sluiter
Feb 11, 2012·The Journal of Alternative and Complementary Medicine : Research on Paradigm, Practice, and Policy·Borja SañudoJoseph G McVeigh
May 1, 2009·American Journal of Physical Medicine & Rehabilitation·Chien-Tsung TsaiChang-Zern Hong
Nov 2, 2012·The Journal of Manual & Manipulative Therapy·Lars Arendt-NielsenThomas Graven-Nielsen
Oct 14, 2010·BMC Musculoskeletal Disorders·Asbjørn T BinderupPascal Madeleine
Nov 10, 2015·The Journal of Pain : Official Journal of the American Pain Society·Lars Henrik LarsenThomas Graven-Nielsen
Jun 19, 2013·The Journal of Pain : Official Journal of the American Pain Society·Stella IacovidesAlison Bentley
Apr 2, 2013·The Journal of Pain : Official Journal of the American Pain Society·Diana E van RooijenJacobus J van Hilten
Jan 10, 2012·The Journal of Pain : Official Journal of the American Pain Society·Siobhan M Schabrun, Paul W Hodges
May 31, 2011·Archives of Physical Medicine and Rehabilitation·Chein-Wei ChangPo-Ling Kuo
Jun 9, 2009·Pathophysiology : the Official Journal of the International Society for Pathophysiology·Juhani V PartanenJari P A Arokoski
Oct 1, 2013·The Journal of Pain : Official Journal of the American Pain Society·Johanna C M SchilderJacobus J van Hilten
Nov 26, 2008·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·D FallaD Farina
Jun 22, 2012·European Journal of Pain : EJP·P J M BankJ J van Hilten
Dec 18, 2010·European Journal of Pain : EJP·Sanna KääriäMikko Laaksonen
Apr 23, 2015·European Journal of Pain : EJP·S IacovidesF C Baker
Jan 29, 2011·Manual Therapy·Daniel Cury RibeiroStephan Milosavljevic
Jan 15, 2015·Archives of Physical Medicine and Rehabilitation·Daniel Pecos-MartínGustavo Plaza-Manzano
Jun 2, 2012·Physiotherapy Canada. Physiothérapie Canada·Catherine Mercier, Guillaume Léonard
Apr 16, 2015·TheScientificWorldJournal·Fernando Kurita VaroliVinícius Pedrazzi
Nov 2, 2016·Journal of Physical Therapy Science·Seong-Uk Go, Byoung-Hee Lee
Apr 3, 2015·Cephalalgia : an International Journal of Headache·Bjarne K MadsenRigmor H Jensen
Jul 29, 2017·Cranio : the Journal of Craniomandibular Practice·Marco Sagripanti, Carlotta Viti
Nov 8, 2018·Journal of Neurophysiology·Christopher J Hasson, Sarah E Goodman
Jul 9, 2011·Journal of Applied Physiology·Serajul I KhanJanet L Taylor
May 17, 2019·Pain·Simon J SummersSiobhan M Schabrun
Jul 30, 2019·Physical Therapy·Thorvaldur S PalssonMervyn Travers
Sep 7, 2016·Hong Kong Physiotherapy Journal : Official Publication of the Hong Kong Physiotherapy Association Limited = Wu Li Chih Liao·Abeer Ahmed Abdelhameed, Amr Almaz Abdel-Aziem
Sep 19, 2009·Journal of Applied Physiology·Lars L AndersenGisela Sjøgaard

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