Muscle quality as a complementary prognostic tool in conjunction with sarcopenia assessment in younger and older individuals

European Journal of Applied Physiology
Matthew J LeesTheocharis Ispoglou

Abstract

This pilot study investigated differences in lean tissue mass, muscle strength, muscle quality (strength per unit of muscle mass; MQ), and functional performance in healthy younger and older individuals. The most robust predictors of appendicular lean mass (ALM) were then determined in each group. Fifty younger (18-45 years) and 50 older (60-80 years) participants completed tests of upper and lower body strength alongside body composition by dual-energy X-ray absorptiometry from which upper- and lower-body MQ were estimated. Available cut-points for older people were used to determine low upper-body MQ in both groups. Low lower-body MQ was determined as at least two standard deviations below the mean of the younger group. Functional performance was assessed by gait speed. Sarcopenia was identified using two established definitions. Upper and lower body strength, ALM, lower-body MQ and gait speed were significantly higher in the younger group (all p < 0.002). Sarcopenia was identified in 2-4% of the older group. Low upper-body MQ was evident in 32% and 42% of the younger and older group, respectively. Low lower-body MQ was observed in 4% of younger participants, and 50% of older participants. In both groups, the most robust pred...Continue Reading

References

Jun 1, 1990·The American Journal of Clinical Nutrition·R B MazessJ Hanson
Aug 1, 1988·The Journal of Hospital Infection·J Cohen
Apr 29, 1998·American Journal of Epidemiology·R N BaumgartnerR D Lindeman
Jul 25, 2000·Journal of Applied Physiology·I JanssenR Ross
Feb 18, 2003·Journal of the American Geriatrics Society·Anne B NewmanUNKNOWN Health Aging And Body Composition Research Group
Aug 6, 2003·Medicine and Science in Sports and Exercise·Cora L CraigPekka Oja
Oct 14, 2003·Journal of Applied Physiology·Fulvio LauretaniLuigi Ferrucci
Apr 7, 2004·Journal of the American Geriatrics Society·Jennifer S BrachUNKNOWN Health, Aging and Body Composition Study Research Group
Apr 9, 2005·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Darren G Candow, Philip D Chilibeck
Jun 24, 2005·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Yocheved Laufer
Feb 4, 2006·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Anne B NewmanTamara B Harris
Jun 1, 2006·Menopause : the Journal of the North American Menopause Society·Corinne E I LebrunSteven W Lamberts
Nov 2, 2006·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Bret H GoodpasterAnne B Newman
Dec 15, 2006·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Anthony P MarshLuigi Ferrucci
Feb 6, 2007·Medicine and Science in Sports and Exercise·Michael N SawkaNina S Stachenfeld
Feb 26, 2008·Journal of Strength and Conditioning Research·Richard W Bohannon
Apr 29, 2008·Journal of Strength and Conditioning Research·Pedro E AlcarazAnthony J Blazevich
Jul 11, 2008·The American Journal of Clinical Nutrition·Evan AtlantisUNKNOWN Florey Adelaide Male Aging Study
Nov 26, 2008·Journal of Sports Sciences·Lex B VerdijkHans H C M Savelberg
Feb 12, 2009·Journal of the American Geriatrics Society·Matteo CesariUNKNOWN Health, Aging and Body Composition Study
Jul 31, 2009·The American Journal of Clinical Nutrition·Olivier BouillanneChristian Aussel
Apr 16, 2010·Age and Ageing·Alfonso J Cruz-JentoftUNKNOWN European Working Group on Sarcopenia in Older People
Feb 16, 2011·Journal of Epidemiology and Community Health·Jan-Magnus KvammeBjarne K Jacobsen
Mar 30, 2011·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Todd M Manini, Brian C Clark
Dec 20, 2011·Medicine and Science in Sports and Exercise·Alisa NanaLouise M Burke
Jan 13, 2012·The Journal of Nutrition, Health & Aging·S Barbat-ArtigasM Aubertin-Leheudre
Apr 4, 2012·Nutrition·Brian C Clark, Todd M Manini
May 19, 2012·Maturitas·Su-Hsin ChangGraham A Colditz
Feb 12, 2013·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·Salah Gariballa, Awad Alessa
Jun 27, 2013·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·D ScottG Jones
Jan 21, 2014·Journal of the American Geriatrics Society·Ann Zenobia MooreLuigi Ferrucci
Apr 1, 2014·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Rachel CooperUNKNOWN MRC National Survey of Health and Development Scientific and Data Collection Team
Jun 7, 2014·International Journal of Sport Nutrition and Exercise Metabolism·Michael TielandJ C van Loon L

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Citations

May 6, 2019·European Journal of Applied Physiology·Matthew J LeesTheocharis Ispoglou
Feb 16, 2020·Journal of Cachexia, Sarcopenia and Muscle·Sophia X SuiJulie A Pasco
May 11, 2019·European Journal of Applied Physiology·Murat KaraLevent Özçakar
Nov 17, 2020·Expert Review of Respiratory Medicine·V K S LageV A Mendonça
Oct 4, 2020·Current Opinion in Supportive and Palliative Care·Ana Paula Trussardi FayhMaria Cristina Gonzalez
Apr 22, 2021·Journal of Clinical Densitometry : the Official Journal of the International Society for Clinical Densitometry·Sophia X SuiJulie A Pasco
Jul 3, 2021·Medicina·Daniel A HackettMaria Fiatarone Singh
Dec 1, 2021·Journal of Cachexia, Sarcopenia and Muscle·Yasunori AkamatsuNoriko Satoh-Asahara
Dec 24, 2021·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Fengyan ChenZheqing Zhang

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Methods Mentioned

BETA
X-ray

Software Mentioned

Lunar enCORE
SPSS

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