Muscle Synergies in Cycling after Incomplete Spinal Cord Injury: Correlation with Clinical Measures of Motor Function and Spasticity

Frontiers in Human Neuroscience
Filipe BarrosoJosé L Pons

Abstract

After incomplete spinal cord injury (iSCI), patients suffer important sensorimotor impairments, such as abnormal locomotion patterns and spasticity. Complementary to current clinical diagnostic procedures, the analysis of muscle synergies has emerged as a promising tool to study muscle coordination, which plays a major role in the control of multi-limb functional movements. Based on recent findings suggesting that walking and cycling share similar synergistic control, the analysis of muscle synergies during cycling might be explored as an early descriptor of gait-related impaired control. This idea was split into the following two hypotheses: (a) iSCI patients present a synergistic control of muscles during cycling; (b) muscle synergies outcomes extracted during cycling correlate with clinical measurements of gait performance and/or spasticity. Electromyographic (EMG) activity of 13 unilateral lower limb muscles was recorded in a group of 10 healthy individuals and 10 iSCI subjects during cycling at four different cadences. A non-negative matrix factorization (NNMF) algorithm was applied to identify synergistic components (i.e., activation coefficients and muscle synergy vectors). Reconstruction goodness scores (VAF and r (2)) ...Continue Reading

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Citations

Dec 21, 2016·Frontiers in Neuroscience·Pieter-Jan MaesMarc Leman
Jun 1, 2018·Applied Bionics and Biomechanics·Rajat Emanuel SinghTarun Edgar Hutchinson
Aug 8, 2020·Frontiers in Bioengineering and Biotechnology·Diego TorricelliJose L Pons
Feb 4, 2021·Journal of Neurophysiology·Lilla BotzheimFilipe Oliveira Barroso
Mar 18, 2021·Journal of Neurophysiology·Vincent C K Cheung, Kazuhiko Seki
Jul 1, 2021·Journal of Neuroengineering and Rehabilitation·Gustavo BalbinotJose Zariffa
Sep 25, 2021·Physiological Reports·Hannah D CareyJessica L Allen
Jul 5, 2021·European Journal of Applied Physiology·Yosra CherniNicolas A Turpin

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Software Mentioned

SENIAM
PENN
MATLAB
HYPER
MOTOmed
SCATS
SPSS Statistics

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