Muscle tensions merge to cause a DNA replication crisis

The Journal of Cell Biology
Daniel BraysonCatherine M Shanahan

Abstract

In this issue, Wang et al. (2018. J. Cell Biol. https://doi.org/10.1083/jcb.201708137) show that disruption to different mechanical domains of muscle cells converge at the linker of nucleoskeleton to cytoskeleton complex to affect DNA endoreplication potentially via barrier to autointegration factor-mediated epigenetic mechanisms.

References

Dec 29, 2005·The Journal of Cell Biology·Melissa CrispDidier Hodzic
Feb 7, 2009·Nature Reviews. Molecular Cell Biology·Ning WangDonald E Ingber
Dec 1, 2009·Journal of Molecular and Cellular Cardiology·Megan J PuckelwartzElizabeth M McNally
Oct 6, 2011·Nucleus·Nikolaj ZulegerEric C Schirmer
Dec 1, 2011·Nucleus·Rocío Montes de OcaKatherine L Wilson
Mar 13, 2014·Nature Cell Biology·Christophe GuilluyKeith Burridge
Dec 18, 2014·Development·Meredith H Wilson, Erika L F Holzbaur
Apr 25, 2017·The Journal of Physiology·Ilse A E BollenJolanda van der Velden
Nov 7, 2017·Cell·Alberto Elosegui-ArtolaPere Roca-Cusachs
Apr 14, 2018·The Journal of Cell Biology·Shuoshuo WangTalila Volk

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Citations

Apr 27, 2019·Frontiers in Cell and Developmental Biology·Tejas DharmarajKatherine L Wilson

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Methods Mentioned

BETA
histone acetylation
optical tweezers
fluorescence imaging
dissection

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