Music Use for Sedation in Critically ill Children (MUSiCC trial): study protocol for a pilot randomized controlled trial

Pilot and Feasibility Studies
Gonzalo Garcia GuerraCanadian Critical Care Trials Group

Abstract

Stress induced by pain and anxiety is common in pediatric intensive care unit (PICU) patients. Sedation/analgesia in PICU is usually achieved through various analgesics and sedatives. Excessive use of these drugs can put patients at risk for hemodynamic/respiratory instability, prolonged ventilation, withdrawal, delirium, and critical illness polyneuromyopathy.The use of non-pharmacologic interventions has been recommended by sedation guidelines. However, non-pharmacological measures in PICU, including music and noise reduction, have been inadequately studied. The Music Use for Sedation in Critically ill Children (MUSiCC trial) pilot study is an investigator-initiated, three-arm, randomized controlled trial (RCT) on the use of music for sedation in PICU. The main goal of the study is to demonstrate feasibility of a music trial in PICU and to obtain the necessary information to plan a larger trial. The study compares music versus noise cancelation versus control in sedated and mechanically ventilated children admitted to PICU. In the music group, children receive the music (modified classical music) three times a day for 30 min at a time. Music is delivered with noise cancelation headphones. The noise cancelation group receives ...Continue Reading

Associated Clinical Trials

Apr 13, 2018·Gonzalo Garcia Guerra

References

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Nov 8, 2012·Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies·Kanwaljeet J S AnandUNKNOWN Human Development (NICHD) Collaborative Pediatric Critical Care Research Network (CPCCRN)
Dec 28, 2012·Critical Care Medicine·Juliana BarrUNKNOWN American College of Critical Care Medicine
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Jul 29, 2016·Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies·Gonzalo Garcia GuerraUNKNOWN Sedation Withdrawal and Analgesia Team, and the Canadian Critical Care Trials Group
Dec 15, 2016·Pilot and Feasibility Studies·Sandra M EldridgeUNKNOWN PAFS consensus group
Dec 24, 2017·Journal of Critical Care·Gonzalo Garcia GuerraUNKNOWN Canadian Critical Care Trials Group (CCCTG)
Jun 16, 2019·Journal of Critical Care·Gonzalo Garcia GuerraUNKNOWN Canadian Critical Care Trials Group

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Citations

Jan 13, 2021·Journal of Intensive Care·Gonzalo Garcia GuerraUNKNOWN Canadian Critical Care Trials Group

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Methods Mentioned

BETA
sedation

Clinical Trials Mentioned

NCT03497559

Software Mentioned

R
REDCap
MUSiCC
Research Electronic Data Capture

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