PMID: 7035917Feb 1, 1982Paper

Mutagen and anti-mutagen in ginger, Zingiber officinale

Mutation Research
H Nakamura, T Yamamoto

Abstract

When rhizome juice of ginger, zingiber officinale, was added to a solution of 2(2-furyl)-3(5-nitro-2-fury)acryl amide (AF2) or N-methyl-N'-nitro-N-nitrosoguanidine (NTG), mutagenesis by these chemicals was markedly increased. As a result of the component fractionation of the ginger juice, it was found that [6]-gingerol was a potent mutagen. However, the ginger juice also contained anti-mutagenic component(s) against [6]-gingerol (CAS No. 58253-27-3) (present study) and tryptophan pyrolysates (Kada et al., 1978; Morita et al., 1978). It is suggested, therefore, that the [6]-gingerol component may be mutagenically activated by the presence of AF2 and NTG.

References

Jan 1, 1964·Biochemical and Biophysical Research Communications·A Zampieri, J Greenberg

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Citations

Sep 1, 1986·Cell Biology and Toxicology·J T ZelikoffS Belman
Jan 4, 1991·European Journal of Obstetrics, Gynecology, and Reproductive Biology·W Fischer-RasmussenU Asping
Apr 1, 1984·Mutation Research·S K Abraham, P C Kesavan
Nov 1, 1983·Mutation Research·H Nakamura, T Yamamoto
May 1, 1986·Mutation Research·Y SakaiF Yamada
Jan 28, 2004·Complementary Therapies in Nursing & Midwifery·Rachel Emma Westfall
Jul 28, 2004·Journal of Herbal Pharmacotherapy·Eric A Jackson
Nov 4, 2010·Journal of Obstetric, Gynecologic, and Neonatal Nursing : JOGNN·Cathi DennehyTekoa L King
Nov 9, 2011·Journal of Midwifery & Women's Health·Cathi Dennehy
Oct 31, 2000·Phytotherapy Research : PTR·M J Mukhopadhyay, A Mukherjee
Sep 11, 2007·Journal of Midwifery & Women's Health·Bryan P Bayles
Aug 1, 2006·Environmental and Molecular Mutagenesis·Lucas Tadeu BidinottoLuís Fernando Barbisan

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