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Mutagen-nucleic acid intercalative binding: structure of a 9-aminoacridine: 5-iodocytidylyl(3'-5')guanosine crystalline complex

Proceedings of the National Academy of Sciences of the United States of America

Jan 1, 1977

T D SakoreHenry M Sobell

PMID: 264674

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Abstract

9-Aminoacridine forms a crystalline complex with the dinucleoside monophosphate, 5-iodocytidylyl(3'-5')guanosine. We have solved the three-dimensional structure of this complex by x-ray crystallography and have observed two distinct intercalative binding modes by this drug to miniature ...read more

Mentioned in this Paper

X-Ray Diffraction
Oligonucleotides
Guanosine
Mutagenesis Process
Nucleic Acids
Acridines
Aminacrine
Frameshift Mutation Function
Crystallography, X-Ray
Neurofibromatosis 1
12
Paper Details
References
  • References18
  • Citations43
12
  • References18
  • Citations43
12345

Mutagen-nucleic acid intercalative binding: structure of a 9-aminoacridine: 5-iodocytidylyl(3'-5')guanosine crystalline complex

Proceedings of the National Academy of Sciences of the United States of America

Jan 1, 1977

T D SakoreHenry M Sobell

PMID: 264674

DOI:

Abstract

9-Aminoacridine forms a crystalline complex with the dinucleoside monophosphate, 5-iodocytidylyl(3'-5')guanosine. We have solved the three-dimensional structure of this complex by x-ray crystallography and have observed two distinct intercalative binding modes by this drug to miniature ...read more

Mentioned in this Paper

X-Ray Diffraction
Oligonucleotides
Guanosine
Mutagenesis Process
Nucleic Acids
12

Related Papers

Paper Details
References
  • References18
  • Citations43
12
  • References18
  • Citations43
12345

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