PMID: 6988705Mar 1, 1980Paper

Mutagenesis by photoaffinity labeling using selected azidofluorenes

Mutation Research
B R BrownW E White

Abstract

Several 2-azidofluorenes have been synthesized for use as photoaffinity labels inside bacteria. In the dark they were not mutagenic for any Salmonella typhimurium tested. When photolyzed inside the bacteria, all were mutagenic for strain TA1538 to varying degrees, and were considerably less mutagenic in the corresponding repair positive TA1978. None were mutagenic for strain TA1535 or TA1537, although most compounds were toxic for those strains when photolyzed.

References

Jul 28, 1978·Biochemical and Biophysical Research Communications·A M SarrifN DiVito
Aug 23, 1976·Biochemical and Biophysical Research Communications·W L Nelson, S S Thorgeirsson
Feb 1, 1977·Journal of Bioenergetics and Biomembranes·C K Kurup, D R Sanadi
Aug 1, 1973·Proceedings of the National Academy of Sciences of the United States of America·B N AmesF D Lee
Sep 9, 1974·Biochimica Et Biophysica Acta·E Kriek
Jun 1, 1980·In Vitro·M D DollingerW E White

Related Concepts

2-azidofluorene
Affinity Labels
Azides
Medicinal Plants Testing, Preclinical
Fluorenes
Genetic Techniques
Clastogens
Salmonella typhimurium LT2

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