Mutagenic activity of airborne particulate matter in a petrochemical industrial area

Mutation Research
Mariana V CoronasVera Maria Ferrão Vargas

Abstract

Exposure to airborne particulate matter has adverse effects on human health and ecosystem. Mutagenic activity of airborne particulate organic matter extracts in three time periods from total suspended particles (TSP) and particles less than 10 microm (PM10) was evaluated in an area under the influence of a petrochemical industry located in the town of Triunfo, Brazil. The extracts were investigated using the Salmonella/microsome assay, with the microsuspension method. The extracts were obtained by sonication extracted using dichloromethane (DCM) solvent. The fractions were tested for mutagenicity with the Salmonella typhimurium strains TA98 (with and without metabolic activation), TA98NR and TA98/1,8DNP(6); or YG1021 and YG1024. A positive frameshift mutagenic response was observed for the environmental samples during the different periods. The responses according to percentage of extractable organic matter (EOM%), EOM/m(3), revertants/microg (rev/microg) and revertants/m(3) (rev/m(3)) were lower for TSP than for PM10 extracts. The highest rev/m(3) values were observed in PM10 extract samples collected in winter, July 2005, in the presence (13.79 rev/m(3)) or absence (6.87 rev/m(3)) of S9 fraction. Similarly in the first (1995)...Continue Reading

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Citations

Sep 7, 2011·Ecotoxicology and Environmental Safety·Thatiana Cappi da CostaVera Maria Ferrão Vargas
Apr 19, 2011·Ecotoxicology and Environmental Safety·Nilmara de Oliveira AlvesSilvia Regina Batistuzzo de Medeiros
Sep 12, 2009·Ecotoxicology and Environmental Safety·Andréia Torres LemosVera Maria Ferrão Vargas
Jan 27, 2009·Mutation Research·Flavio Manoel Rodrigues da Silva Júnior, Vera Maria Ferrão Vargas
Feb 15, 2014·Environmental Research·Nilmara de Oliveira AlvesSilvia Regina Batistuzzo de Medeiros
Apr 13, 2011·Environmental Research·Sandro José de AndradeEliana Aparecida Varanda
Nov 21, 2014·Environmental Science and Pollution Research International·D D MeyerV M F Vargas
Jul 17, 2012·Chemosphere·Andréia Torres LemosVera Maria Ferrão Vargas
Aug 23, 2018·Anais Da Academia Brasileira De Ciências·Natália Mossmann KochVera Maria Ferrão Vargas

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