PMID: 7521013Sep 1, 1994Paper

Mutagenic evaluation of primaquine, pentaquine and pamaquine in the Salmonella/mammalian microsome assay

Mutation Research
T OnoH Yoshimura

Abstract

The 8-aminoquinolines, primaquine, pentaquine and pamaquine, were investigated for mutagenic activity in Salmonella typhimurium strains TA100, TA98, TA97 and TA102 in the rat liver microsomal activation system. Primaquine and pentaquine induced mutations in TA97 in the presence and absence of S9 mix. Pamaquine was mutagenic to TA98 only in the absence of S9 mix.

References

Dec 1, 1975·Proceedings of the National Academy of Sciences of the United States of America·J McCannB N Ames
Aug 1, 1973·Proceedings of the National Academy of Sciences of the United States of America·B N AmesF D Lee
May 1, 1983·Mutation Research·D M Maron, B N Ames

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Citations

Oct 1, 1998·Toxicology in Vitro : an International Journal Published in Association with BIBRA·F FontaineR Rahmani
Jun 17, 2004·Drug and Chemical Toxicology·Ahmed MaslatMahmoud el-Talib
Mar 17, 2007·Drug and Chemical Toxicology·Ahmed O MaslatGhassan Abu Sheikha
Apr 13, 2012·Travel Medicine and Infectious Disease·Remington L Nevin
Jan 29, 2002·Environmental and Molecular Mutagenesis·Tomoko Ono-OgataHideo Yamagata
Jul 15, 2021·Journal of Toxicology·Klaus M BeckerFrancisco J R Paumgartten

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