PMID: 1881415Sep 11, 1991Paper

Mutagenicity of wood smoke condensates in the Salmonella/microsome assay

Mutation Research
A O AsitaH Matsushita

Abstract

Smoke condensates of woods used for food preservation and aromatization in Nigeria were tested for mutagenic activity using Salmonella typhimurium TA98 and TA100. The woods were: white mangrove (Avicennia nitida), red mangrove (Rhizophora racemosa), mahogany Khaya sp.), abura (Mitragyna ciliata), alstonia (Alstonia boonei) and black afara (Terminalia ivorensis). Cigarette tar was tested for comparison. The condensates induced dose-dependent increases in the number of His+ revertants mainly with S9 mix. With the exception of mahogany and cigarette smoke condensate, the smoke condensates induced more revertants/microgram condensate in TA100 than in TA98. The number of revertants/microgram condensate ranged between 0.04 and 0.9 for the wood smoke condensates and was 0.12 for the cigarette smoke in TA100. The range was between 0.1 and 0.30 for the wood smoke condensates and 0.18 revertants/microgram condensate for cigarette smoke condensate in TA98. Concentrations of 7 polycyclic aromatic hydrocarbons (PAHs) in the condensates were determined namely, pyrene, benzo[a]pyrene, benz[a]anthracene, benzo[k]fluoranthene, benzo[b]chrysene, benzo[g,h,i]perylene and dibenzo[a,e]pyrene. The condensates contained varying concentrations of the ...Continue Reading

References

Jan 1, 1977·Mutation Research·P Brookes
Apr 1, 1979·Food and Cosmetics Toxicology·K MossandaM Mercier
Dec 1, 1975·Proceedings of the National Academy of Sciences of the United States of America·J McCannB N Ames
Jan 9, 1987·Science·J L MumfordJ C Chuang
Apr 1, 1968·Chemical Reviews·R L Stedman
May 1, 1983·Mutation Research·D M Maron, B N Ames
Aug 1, 1988·Environmental Science & Technology·C W LewisJ Lewtas

❮ Previous
Next ❯

Citations

Sep 1, 1994·Mutation Research·B NardiniE Clonfero
Aug 15, 1994·The Science of the Total Environment·A Abe, K Urano
Feb 14, 2016·Bioscience, Biotechnology, and Biochemistry·Aya OnodaHaruo Nukaya
Mar 27, 2012·Environmental Toxicology and Pharmacology·Atif KamalAudil Rashid
Dec 3, 2014·The Science of the Total Environment·Aleksandra JedynskaIngeborg M Kooter
Nov 21, 2014·Environmental Science and Pollution Research International·Atif KamalRiffat Naseem Malik
May 8, 2016·Journal of Ethnopharmacology·Ashutosh SharmaMaría Luisa Villarreal
Dec 2, 2004·Mutation Research·David M DeMarini
Nov 28, 2006·Inhalation Toxicology·Luke P NaeherKirk R Smith
Dec 1, 2008·Toxicological Research·Young-Shin ChungMichael Lee

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.