PMID: 11916127Mar 28, 2002Paper

Mutant laboratory mice with abnormalities in pigmentation: annotated tables

Journal of Dermatological Science
M NakamuraRalf Paus

Abstract

Mammalian pigment cell research has recently entered a phase of significantly increased activity due largely to the exploitation of the many mutant mouse stocks that are coming on stream. Numerous transgenic, targeted mutagenesis (so-called 'knockouts'), conditional (so-called 'gene switch') and spontaneous mutant mice develop abnormal coat color phenotypes. The number of mice that exhibit such abnormalities is increasing exponentially as genetic engineering methods become routine. Since defined abnormalities in such mutant mice provide important clues to the as yet often poorly understood functional roles of many gene products, this overview includes a corresponding, annotated table of mutant mice with pigmentation alterations. These range from early developmental defects via a large array of coat color abnormalities to a melanoma metastasis model. This overview should provide helpful pointers to investigators who are looking for mouse models to explore or to compare functional activities of genes of interest and for comparing coat color phenotypes of spontaneous or genetically engineered mouse mutants with novel ones. Secondly, this review includes a table of mouse models of specific human diseases with genetically defined pi...Continue Reading

References

Jun 1, 1992·Experimental Cell Research·T IwamotoI Nakashima
Jan 1, 1991·Proceedings of the National Academy of Sciences of the United States of America·M BradlB Mintz
May 1, 1991·Proceedings of the National Academy of Sciences of the United States of America·M KlüppelG Schütz
Oct 1, 1991·The Journal of Investigative Dermatology·A SlominskiJ Wortsman
Nov 1, 1991·Proceedings of the National Academy of Sciences of the United States of America·B Mintz, M Bradl
Oct 1, 1990·Proceedings of the National Academy of Sciences of the United States of America·S L MansourM R Capecchi
Mar 1, 1989·Proceedings of the National Academy of Sciences of the United States of America·R VassarE Fuchs
Oct 1, 1981·Proceedings of the National Academy of Sciences of the United States of America·T E WagnerJ B Gault
May 23, 1995·Proceedings of the National Academy of Sciences of the United States of America·M L KlebigR P Woychik
Jan 1, 1994·Annual Review of Genetics·I J Jackson
Jun 1, 1994·The Journal of Investigative Dermatology·A SlominskiS Lukiewicz
Jun 7, 1994·Proceedings of the National Academy of Sciences of the United States of America·H VrielingG S Barsh
Jan 1, 1993·International Review of Cytology·D C Bennett
May 1, 1996·Journal of the American Academy of Dermatology·D S RigelA W Kopf
Jun 11, 1996·Proceedings of the National Academy of Sciences of the United States of America·H TakayamaG Merlino
Aug 1, 1996·The Journal of Clinical Investigation·K RajewskyF Schwenk
Oct 1, 1996·Developmental Dynamics : an Official Publication of the American Association of Anatomists·H YoshidaT Kunisada
Jan 21, 1997·Proceedings of the National Academy of Sciences of the United States of America·H TakayamaG Merlino
Jan 1, 1997·Human Molecular Genetics·I J Jackson
Nov 14, 1997·Genes & Development·L ChinR A DePinho
Feb 6, 1999·International Journal of Cancer. Journal International Du Cancer·A SchmidtF Beermann
Aug 10, 1999·Nature·L ChinR A DePinho
Sep 2, 1999·Carcinogenesis·M Broome PowellG T Bowden
Jun 7, 2000·Pigment Cell Research·S Jordan, F Beermann
Jul 6, 2000·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·E C Dell'AngelicaJ S Bonifacino
Aug 30, 2000·Proceedings of the National Academy of Sciences of the United States of America·K J DunnW J Pavan
Feb 13, 2001·Experimental Gerontology·D J Tobin, R Paus
Jun 19, 2001·Genes & Development·C A CroninH Scrable
Jul 10, 2001·The Journal of Investigative Dermatology·S Müller-RöverR Paus

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Citations

Jul 17, 2008·Comparative and Functional Genomics·Vicky TsipouriIan C Gray
Oct 21, 2010·Pigment Cell & Melanoma Research·Karin U SchallreuterHartmut Rokos
Nov 13, 2010·Pigment Cell & Melanoma Research·Desmond J Tobin
Nov 27, 2010·Pigment Cell & Melanoma Research·Ralf Paus
Jul 14, 2004·Proceedings of the National Academy of Sciences of the United States of America·Shoji FukamachiAkihiro Shima
Nov 21, 2012·Journal of Dermatological Science·Motonobu NakamuraRalf Paus
Dec 31, 2005·The Journal of Investigative Dermatology. Symposium Proceedings·John P SundbergRalf Paus
Jan 19, 2005·The Journal of Investigative Dermatology·Andrzej SlominskiDesmond J Tobin
Nov 10, 2007·Veterinary Dermatology·Kangseok SeoInho Hwang
Mar 18, 2004·Animal Genetics·R B TerryE Bailey
Aug 21, 2008·International Journal of Cosmetic Science·D J Tobin
Sep 30, 2004·Mechanisms of Development·Brigitte L Arduini, Paul D Henion
May 13, 2009·Developmental Biology·Nicolas Gompel, Benjamin Prud'homme
Jul 28, 2016·Cellular and Molecular Life Sciences : CMLS·Carmen Ehrmann, Marlon R Schneider
Jan 1, 2013·Journal of Toxicologic Pathology·Lars MecklenburgAlys Bradley
Oct 23, 2020·Pigment Cell & Melanoma Research·Grégoire BonnamourNicolas Pilon
Nov 30, 2005·Development·Masatake OsawaShin-Ichi Nishikawa

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