Mutation of a mitochondrial outer membrane protein affects chloroplast lipid biosynthesis

The Plant Journal : for Cell and Molecular Biology
Changcheng XuC Benning

Abstract

Lipid biosynthesis in plant cells is associated with various organelles, and maintenance of cell lipid homeostasis requires nimble regulation and coordination. In plants, environmental cues such as phosphate limitation require readjustment of the lipid biosynthetic machinery to substitute phospholipids by non-phosphorous glycolipids. Biosynthesis of the galactoglycerolipids predominant in plants proceeds by a constitutive and an alternative pathway that is known to be induced in response to phosphate deprivation. Plant lipid galactosyltransferases involved in both pathways are associated with the plastid envelope membranes and are encoded by nuclear genes. To identify mechanisms governing the activity of the alternative galactoglycerolipid pathway, a genetic suppressor screen was conducted in the background of the digalactolipid-deficient dgd1 mutant of Arabidopsis. A suppressor line that partially restored digalactoglycerolipid content in the dgd1 background carries a point mutation in a mitochondrial protein, which was tentatively designated DGD1 SUPPRESSOR 1 (DGS1). Presumed orthologs of this protein are present in plants, algae and fungi, but its molecular function is not yet known. In the dgd1 dgs1 double mutant, expressio...Continue Reading

References

Aug 17, 1972·Biochimica Et Biophysica Acta·R DouceW D Bonner
Aug 1, 1993·The Plant Journal : for Cell and Molecular Biology·A Konieczny, F M Ausubel
Sep 1, 1997·Nucleic Acids Research·S F AltschulD J Lipman
Mar 21, 1998·Proceedings of the National Academy of Sciences of the United States of America·B EssigmannC Benning
Mar 9, 1999·The Plant Journal : for Cell and Molecular Biology·S J Clough, A F Bent
Nov 26, 1999·The Plant Journal : for Cell and Molecular Biology·J F Martínez-GarcíaP H Quail
Sep 6, 2000·Proceedings of the National Academy of Sciences of the United States of America·H HärtelC Benning
Mar 22, 2002·Trends in Plant Science·Peter Dörmann, Christoph Benning
Feb 1, 1993·Plant Physiology·M. E. Theodorou, W. C. Plaxton
May 14, 2003·The EMBO Journal·Changcheng XuChristoph Benning
Jun 3, 2004·Proceedings of the National Academy of Sciences of the United States of America·Ryoung Shin, Daniel P Schachtman
Dec 1, 2004·The Journal of Cell Biology·Juliette JouhetMaryse A Block
Dec 14, 2004·The Journal of Biological Chemistry·Christoph Benning, Hiroyuki Ohta
Apr 5, 2005·Nature Genetics·Markus SchmidJan U Lohmann
May 17, 2005·Proceedings of the National Academy of Sciences of the United States of America·Kenji MiuraPaul M Hasegawa
Aug 9, 2005·Proceedings of the National Academy of Sciences of the United States of America·Julie MissonMarie-Christine Thibaud
Nov 19, 2005·Proteomics·Simone SchmittDoron Rapaport
Nov 24, 2005·Current Biology : CB·Hiroaki FujiiJian-Kang Zhu
Jan 3, 2006·The Plant Cell·Tzyy-Jen ChiouChun-Lin Su
May 9, 2006·Plant Physiology·Rajendra BariWolf-Rüdiger Scheible
Jun 10, 2006·The Plant Journal : for Cell and Molecular Biology·Koichi KobayashiHiroyuki Ohta
Jul 5, 2006·Proceedings of the National Academy of Sciences of the United States of America·Koichiro AwaiChristoph Benning
Sep 15, 2006·Progress in Lipid Research·Juliette JouhetMaryse A Block

❮ Previous
Next ❯

Citations

Jul 4, 2009·Annual Review of Cell and Developmental Biology·Christoph Benning
Dec 15, 2010·Trends in Plant Science·Eric R Moellering, Christoph Benning
Feb 3, 2009·Plant Physiology and Biochemistry : PPB·Yuki NakamuraHiroyuki Ohta
Apr 29, 2008·Progress in Lipid Research·Christoph Benning
Oct 27, 2015·Frontiers in Plant Science·Krzysztof Bobik, Tessa M Burch-Smith
Nov 7, 2016·Journal of Experimental Botany·Judith Van DingenenDirk Inzé
Jan 29, 2019·Plant & Cell Physiology·A A Lavell, C Benning
May 13, 2009·Current Opinion in Lipidology

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.