Mutations of N-ras oncogene in myelodysplastic syndromes and leukemias detected by polymerase chain reaction

Japanese Journal of Cancer Research : Gann
H ManoF Takaku

Abstract

By using polymerase chain reaction and differential hybridization, point mutations of N-ras oncogene were investigated among 43 patients with hematopoietic malignancies. Six cases were revealed to carry mutational N-ras oncogenes. One case with acute myelocytic leukemia was found to carry a mutation at codon 13, although this case was in complete remission.

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Jan 1, 1993·Cancer Genetics and Cytogenetics·A M MansoorP B Murthy
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Methods Mentioned

BETA
PCR
MDS

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