Mutations to spectinomycin resistance which alleviate the restriction of an amber suppressor by streptomycin resistance.

Journal of Bacteriology
M KuwanoY Ohnishi

Abstract

Unlike mutations to streptomycin resistance, which restrict the function of an SU II amber suppressor, mutations to spectinomycin resistance have no restrictive effect. Furthermore, mutations to spectinomycin resistance counteract the restrictive action of streptomycin-resistant mutations when combined in a single strain. The mutations to drug resistance, singly or in combination, do not themselves lead to any detectable suppressor activity. The effects on SU II are interpreted in terms of interactions between ribosomal elements.

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Citations

Sep 29, 1975·Molecular & General Genetics : MGG·W PiepersbergH G Wittmann
Jan 1, 1982·Molecular & General Genetics : MGG·T M HenkinG H Chambliss
Jan 1, 1976·Journal of Bacteriology·Y Miyoshi, H Yamagata
Jan 1, 1984·Journal of Bacteriology·T M Henkin, G H Chambliss
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Sep 1, 1970·Bacteriological Reviews·M Nomura
Nov 1, 1969·Journal of Bacteriology·P Anderson
Sep 1, 1983·Journal of Bacteriology·L G MarkE A Morgan
Feb 1, 1972·Journal of Bacteriology·G Kreider, B L Brownstein
Jan 28, 1972·Journal of Molecular Biology·H Yamagata, H Uchida
Feb 20, 1990·Journal of Molecular Biology·M I OakesJ A Lake
Aug 5, 1974·Biochemical and Biophysical Research Communications·A BollenG Lapalme

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