PMID: 6110709Jun 1, 1980Paper

Myasthenic syndrome: effect of choline, plasmapheresis and tests for circulating factor

Journal of Neurology, Neurosurgery, and Psychiatry
H KranzW Gay

Abstract

In a patient with myasthenic syndrome neuro-muscular transmission was characterised by depression and facilitation. The relative extent of these two processes varied between muscles, and in the one muscle with time. Guanidine HCl treatment corrected the electrophysiological defect. Oral choline increased muscle action potential amplitude in response to single shocks. Intravenous choline produced features indicating cholinergic autonomic stimulation. Pimozide and plasmapheresis had no effect. Animal in-vivo and in-vitro studies performed to detect a circulating factor which interferes with neuro-muscular transmission were negative.

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Citations

May 1, 1997·Muscle & Nerve·M M RichS J Bird
Apr 15, 2000·Journal of Clinical Apheresis·R Weinstein
Aug 1, 1984·Journal of Neurology, Neurosurgery, and Psychiatry·D A IngramM Swash
Jun 23, 2010·Journal of Clinical Apheresis·Zbigniew M SzczepiorkowskiUNKNOWN Apheresis Applications Committee of the American Society for Apheresis
Jan 1, 1986·Clinical Neurology and Neurosurgery·M S van der Knaap, R H Derksen
Jan 1, 1983·Vox Sanguinis·M S Kennedy, R E Domen
Jun 21, 2016·Journal of Clinical Apheresis
Mar 1, 1987·The Journal of Allergy and Clinical Immunology·T J Maher
Jun 1, 1985·Annals of Neurology·C PriorJ Newsom-Davis
Aug 12, 1983·Science·J K Blusztajn, R J Wurtman

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