PMID: 9175477May 1, 1997Paper

Myc target genes

Trends in Biochemical Sciences
Carla Grandori, R N Eisenman

Abstract

The myc family of proto-oncogenes belongs to the basic helix-loop-helix leucine-zipper (bHLHZ) class of transcription factors. Myc proteins function as transcriptional activators through heterodimerization with Max, but might also act as negative regulators of transcription. Identification of genes directly controlled by Myc-Max has proved difficult, but recent work is producing a growing list of candidates. Results to date suggest that Myc-Max influences cell growth and proliferation through direct activation of genes involved in DNA synthesis, RNA metabolism and cell-cycle progression.

Citations

Mar 29, 2001·International Journal of Cancer. Journal International Du Cancer·K NishinoS Hayashi
Aug 24, 2000·International Journal of Cancer. Journal International Du Cancer·A PajicD Eick
Oct 3, 2000·Journal of Physiology and Biochemistry·E RocheB Soria
May 1, 1999·Trends in Genetics : TIG·C W Greider
Nov 27, 2001·Lung Cancer : Journal of the International Association for the Study of Lung Cancer·L Mao
Apr 25, 2003·Lung Cancer : Journal of the International Association for the Study of Lung Cancer·Montserrat Sanchez-Cespedes
Nov 6, 2002·Biochimica Et Biophysica Acta·Niall O'Donnell
Sep 18, 1998·Biochimica Et Biophysica Acta·Y SekidoJ D Minna
Jun 26, 1999·Biochimica Et Biophysica Acta·K P Foley, R N Eisenman
Jul 18, 2002·Gene·Oren SchuldinerNissim Benvenisty
Feb 26, 2000·Gene·E BártováI Koutná
Apr 27, 1999·The International Journal of Biochemistry & Cell Biology·B Raught, A C Gingras
Dec 11, 1999·Mutation Research·G FuhrmannG Krupitza
Jan 29, 2000·Mutation Research·C Cerni
Mar 22, 2001·The Plant Journal : for Cell and Molecular Biology·M OhgishiT Aoyama
Aug 3, 2002·European Journal of Biochemistry·Elissavet HatziTheodore Fotsis
May 4, 1999·The Journal of Experimental Medicine·Y Sun, E A Clark
Jul 6, 2000·DNA and Cell Biology·S Aubry, J Charron
Nov 26, 1999·Journal of Interferon & Cytokine Research : the Official Journal of the International Society for Interferon and Cytokine Research·N D LeeL Naumovski
Jan 5, 2001·Nucleic Acids Research·M SchuhmacherD Eick
Jan 21, 2003·Genes & Development·Fionnuala MorrishDavid Hockenbery
Jul 5, 2003·Genes & Development·Carla GrandoriRaymond J Monnat
Jun 24, 1998·Genes & Development·J WangG J Hannon
Jun 29, 1999·Cold Spring Harbor Symposia on Quantitative Biology·G A McArthurR N Eisenman
Apr 25, 2000·Molecular and Cellular Biology·E Santoni-RugiuJ Lukas
Jul 13, 2000·Molecular and Cellular Biology·L J WoodL M Resar

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.