Mycangimycin, a polyene peroxide from a mutualist Streptomyces sp.

Organic Letters
Dong-Chan OhJon Clardy

Abstract

A mutualist actinomycete of the southern pine beetle, Dendroctonus frontalis, produces a polyene peroxide with pronounced antifungal activity. Its structure, absolute configuration, and biological activity were determined by spectral analysis, chemical modification followed by the modified Mosher method, and growth inhibitory assays, respectively.

References

Aug 22, 2003·Nature·U Eckstein-LudwigS Krishna
Jun 2, 2004·Medicinal Research Reviews·Yuanqing TangJonathan L Vennerstrom
Jul 29, 2004·Current Medicinal Chemistry·Valeria CostantinoOrazio Taglialatela-Scafati
Aug 20, 2004·Nature·Jonathan L VennerstromWilliam N Charman
Mar 9, 2005·Current Biology : CB·Martin KaltenpothErhard Strohm
May 7, 2005·The Journal of Organic Chemistry·Félix FreireRicardo Riguera
Nov 23, 2006·Antimicrobial Agents and Chemotherapy·Mary Lynn BanieckiJon Clardy
Oct 4, 2008·Science·Jarrod J ScottCameron R Currie
Aug 1, 1996·Journal of Chemical Ecology·K D KlepzigK F Raffa

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Citations

Jan 31, 2013·Journal of Agricultural and Food Chemistry·Ying-lao ZhangJia-dong Xu
Jun 28, 2011·Journal of Natural Products·M A Mojid MondolHee Jae Shin
Dec 6, 2012·The Journal of Antibiotics·Mohamad Abdul Mojid MondolHee Jae Shin
Mar 25, 2011·Nature Chemistry·Mohammad R SeyedsayamdostJon Clardy
Mar 31, 2009·Nature Chemical Biology·Dong-Chan OhJon Clardy
May 20, 2011·Chemical Communications : Chem Comm·Jason M Crawford, Jon Clardy
Jun 16, 2010·Proceedings of the National Academy of Sciences of the United States of America·Joshua A V BlodgettJon Clardy
Dec 1, 2011·Microbiology and Molecular Biology Reviews : MMBR·P Frey-KlettA Sarniguet
Aug 8, 2013·The Journal of Antibiotics·Timothy R RamadharJon Clardy
Oct 22, 2013·World Journal of Microbiology & Biotechnology·Hongming TanLixiang Cao
Feb 6, 2014·Biometals : an International Journal on the Role of Metal Ions in Biology, Biochemistry, and Medicine·Jun WangLixiang Cao
Oct 12, 2012·Fitoterapia·Xiaofang WuZhiyong Xie
Jun 20, 2013·Journal of Chemical Ecology·Sabrina Koehler, Martin Kaltenpoth
Oct 6, 2015·Journal of Industrial Microbiology & Biotechnology·Michael J SmanskiLinda L Kinkel
Dec 15, 2015·Applied Microbiology and Biotechnology·Aileen BerasateguiMartin Kaltenpoth
Apr 19, 2011·Current Opinion in Biotechnology·Jonathan O'Brien, Gerard D Wright
Apr 21, 2009·Trends in Microbiology·Duur K AanenMichael J Wingfield
Oct 27, 2009·Trends in Microbiology·Martin Kaltenpoth
Aug 21, 2012·Critical Reviews in Microbiology·Kavita Tiwari, Rajinder K Gupta
Nov 19, 2011·FEMS Microbiology Reviews·Ryan F SeipkeMatthew I Hutchings
Jun 9, 2015·Frontiers in Chemistry·David J Newman, Gordon M Cragg
Apr 16, 2015·The Journal of Antibiotics·Charlotte NirmaDidier Stien
Nov 27, 2014·Probiotics and Antimicrobial Proteins·Yu ZhangLixiang Cao
Apr 28, 2016·Journal of Bioscience and Bioengineering·Vartika Srivastava, Ashok K Dubey
Oct 29, 2015·Annals of the New York Academy of Sciences·Victoria L Challinor, Helge B Bode
Feb 17, 2017·Organic Letters·Christine BeemelmannsJon Clardy
Apr 20, 2017·Organic & Biomolecular Chemistry·Yong Sheng XiaoHui Ming Ge
May 19, 2017·FEMS Microbiology Reviews·Anne van der MeijGilles P van Wezel
Jul 27, 2017·Chemical Society Reviews·Ethan B Van ArnamJon Clardy
Nov 4, 2017·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Vera A Vil'Alexander O Terent'ev
Apr 22, 2015·Natural Product Reports·Laura V FlórezMartin Kaltenpoth
Nov 15, 2017·Journal of Chemical Ecology·Emily MeversJon Clardy

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Methods Mentioned

BETA
gradient
total correlation spectroscopy
NMR

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