Mycobacterial chylous ascites: report of three cases and systematic review

Therapeutic Advances in Infectious Disease
Bipadabhanjan MallickVishal Sharma

Abstract

Chylous ascites is an uncommon presentation of mycobacterial infection. We report three cases of tubercular chylous ascites, and in addition, we performed a systematic review of the published literature for the clinical presentation, treatment, and outcomes of mycobacterial chylous ascites. We followed the PRISMA guidelines for the systematic review. A total of 33 cases (including three of ours) were included. The mean age of the reported cases was 32.54 ± 17.56 years, and a male predominance (76%) was noted. The predominant clinical features were abdominal distension, abdominal pain, fever and loss of appetite and weight. Mycobacterium tuberculosis (MTB) and Mycobacterium avium-intracellulare (MAC) infection were responsible for 16 and 15 cases, respectively. All patients with MAC related chylous ascites had HIV infection. The mechanisms were related to lymph nodal enlargement, constrictive pericarditis and remote scrofuloderma. Overall, there was 29% mortality. Use of anti-mycobacterial therapy with use of total parenteral nutrition, octreotide and medium chain triglyceride-based diet resulted in improvement in the rest of the cases. The cause of death in our case was anti-tubercular therapy-induced hepatitis; three deaths we...Continue Reading

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Citations

Sep 24, 2020·Veterinary Clinical Pathology·India PaharsinghIndira Pargass
Jun 28, 2020·Diagnostic Cytopathology·Swati SatturwarSara E Monaco

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Methods Mentioned

BETA
biopsy
X ray
PCR

Software Mentioned

EMBASE

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