Mycobacteriophages: an important tool for the diagnosis of Mycobacterium tuberculosis (review)

Molecular Medicine Reports
Xiaoyan FuJicheng Li

Abstract

The prevention and control of tuberculosis (TB) on a global scale has become increasingly important with the emergence of multidrug‑resistant TB. Mycobacterium tuberculosis phages have been identified as an important investigative tool. Phage genomes exhibit a significant level of diversity and mosaic genome architecture, however, they are simple structures, which are amenable to genetic manipulation. Based on these characteristics, the phages may be used to construct a shuttle plasmid, which is an indispensable tool in the investigation of TB. Furthermore, they may be used for rapid diagnosis and assessing drug susceptibility of TB, including phage amplified assessment and reporter phage technology. With an improved understanding of mycobacteriophages, further clarification of the pathogenesis of TB, and of the implications for its diagnosis and therapy, may be elucidated.

References

Apr 25, 1991·Proceedings of the National Academy of Sciences of the United States of America·M H LeeG F Hatfull
Mar 1, 1989·Reviews of Infectious Diseases·W R JacobsB R Bloom
Sep 1, 1988·Proceedings of the National Academy of Sciences of the United States of America·S B SnapperW R Jacobs
Oct 17, 1970·Nature·C V Raj, T Ramakrishnan
Aug 1, 1980·Antimicrobial Agents and Chemotherapy·H L DavidJ Moniz-Pereira
Oct 6, 1997·Proceedings of the National Academy of Sciences of the United States of America·S BardarovW R Jacobs
Jun 24, 1998·Journal of Molecular Biology·M E FordG F Hatfull
Jan 25, 2000·Tubercle and Lung Disease : the Official Journal of the International Union Against Tuberculosis and Lung Disease·M E FordG F Hatfull
Jun 19, 2002·The International Journal of Tuberculosis and Lung Disease : the Official Journal of the International Union Against Tuberculosis and Lung Disease·H AlbertL Blumberg
Mar 27, 2003·Molecular Microbiology·Christopher M SassettiEric J Rubin
Apr 5, 2003·Journal of Medical Microbiology·Ayman Mohamed MareiAfify Fahmy Afify
Jul 5, 2003·Journal of Clinical Microbiology·Fernando AlcaideRogelio Martín
Jan 1, 1964·The Journal of Experimental Medicine·T TOKUNAGA, M SELLERS
Feb 1, 1965·Journal of Bacteriology·T TOKUNAGA, M I SELLERS
Jan 29, 2008·BMC Infectious Diseases·Rosemary E WeirHazel M Dockrell
Feb 15, 2008·Journal of Microbiological Methods·Azger DusthackeerNarayanan Paranji Rama
Oct 1, 1947·Proceedings of the Society for Experimental Biology and Medicine·G M GARDNER, R S WEISER
Jun 15, 2010·The Journal of Antimicrobial Chemotherapy·Kwok Chiu ChangRaphael Chiu Yeung Chan
Feb 25, 2011·Journal of Clinical Microbiology·Liliana RondónHoward E Takiff
Aug 19, 2011·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·V N A DusthackeerV Kumar
Jan 1, 2011·Tuberculosis Research and Treatment·Kazuhiro Matsuo, Yasuhiro Yasutomi
May 9, 2013·FEMS Microbiology Letters·Joas L da SilvaMario H Hirata
Jul 16, 2013·Applied and Environmental Microbiology·Mariana PiuriGraham F Hatfull

❮ Previous
Next ❯

Citations

Mar 8, 2018·Archives of Virology·Takako UjiharaShigenobu Matsuzaki
Jun 23, 2018·Genome Announcements·Jumpei UchiyamaMasahiro Sakaguchi
Jul 20, 2016·International Journal of Molecular Medicine·Zhang BaoJianying Zhou

❮ Previous
Next ❯

Related Concepts

Related Feeds

Bacteriophage: Phage Therapy

Phage therapy uses bacterial viruses (bacteriophages) to treat bacterial infections and is widely being recognized as an alternative to antibiotics. Here is the latest research.