Mycobacterium avium subspecies paratuberculosis - an important food borne pathogen of high public health significance with special reference to India: an update

The Veterinary Quarterly
Kundan K ChaubeyKuldeep Dhama

Abstract

This review underlines the public health significance of 'Indian Bison Type' of Mycobacterium avium subspecies paratuberculosis (MAP) and also its potential as 'zoonotic infection'. In the absence of control programs, bio-load of MAP is increasing and if we take total population of animals (500 million plus) and human beings (1.23 billion plus) into account, the number of infected animals and human beings will run into millions in India. Our research on screening of over 26,000 domestic livestock for MAP infection using 4 different diagnostic tests (microscopy, culture, ELISA and PCR), during last 31 years has shown that the average bio-load of MAP in the livestock population of India is very high (cattle 43%, buffaloes 36%, goats 23% and sheep 41%). 'Mass screening' of 28,291 human samples between 2008-2016 revealed also high bio-load of MAP. It has been proved that MAP is not in-activated during pasteurization and therefore live bacilli are continuously reaching human population by consumption of even pasteurized milk and other milk products. Live bacilli have also been recovered from meat products and the environment thus illustrating the potential of MAP as pathogen of public health concern. However, at present, there is in...Continue Reading

References

Jun 1, 1978·Social Science & Medicine·J F Mayberry, R A Hitchens
Aug 1, 1992·Journal of Autoimmunity·M G DanieliA Gabrielli
Jan 1, 1992·Journal of Clinical Microbiology·R W SweeneyA E Rosenberger
Dec 1, 1989·Diseases of the Colon and Rectum·T K Dalziel
Nov 1, 1985·The Journal of Pediatrics·E B Blau
Oct 1, 1993·Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·R J Chiodini, J Hermon-Taylor
Feb 1, 1993·Gastroenterology·J Hermon-Taylor
Feb 1, 1996·Applied and Environmental Microbiology·I R GrantM T Rowe
Jul 5, 1996·International Journal of Cardiology·A AggarwalS Naik
Sep 1, 1997·Infection and Immunity·J D CirilloL E Bermudez
Jan 22, 1998·Journal of Dairy Science·M T Collins
Mar 21, 1998·Applied and Environmental Microbiology·N Sung, M T Collins
Aug 26, 1998·Journal of Food Protection·J Keswani, J F Frank
Apr 14, 2000·The American Journal of Gastroenterology·S A NaserI Shafran
Jul 11, 2000·Canadian Journal of Gastroenterology = Journal Canadien De Gastroenterologie·J Hermon-TaylorN Sumar
Oct 6, 2000·Annual Review of Microbiology·U SzewzykK H Schleifer
May 26, 2001·Applied and Environmental Microbiology·N J RowanO Farish
Jun 22, 2002·International Journal of Food Microbiology·Barbara M LundAnita M Rampling
Dec 19, 2002·Journal of Dairy Science·S S NielsenC Enevoldsen
Jan 7, 2003·Journal of Dairy Science·A GaoJ Odumeru
Apr 23, 2003·Preventive Veterinary Medicine·Joan KlausenPeter Ahrens
Apr 25, 2003·Journal of Veterinary Medicine. B, Infectious Diseases and Veterinary Public Health·F A PaolicchiiM Romano
Jan 27, 2004·Journal of Dairy Science·J E MuehlherrR Stephan
Aug 6, 2004·Applied and Environmental Microbiology·J A DonaghyM T Rowe
Feb 11, 2005·Journal of the American Veterinary Medical Association·Steven H HendrickMarie Archambault
Apr 7, 2005·Applied and Environmental Microbiology·Jamie S YoungElizabeth M H Wellington

❮ Previous
Next ❯

Citations

Jul 9, 2020·Microorganisms·Julius Boniface OkuniLonzy Ojok
Oct 7, 2020·Animals : an Open Access Journal From MDPI·Mary Garvey
Oct 20, 2019·Microorganisms·Coad Thomas Dow, Leonardo A Sechi
Mar 6, 2021·Journal of Translational Autoimmunity·Coad Thomas Dow, Edward D Chan
Jun 9, 2019·Comparative Immunology, Microbiology and Infectious Diseases·Manju SinghJagdip Singh Sohal

❮ Previous
Next ❯

Methods Mentioned

BETA
PCR
ELISA
light microscopy

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

© 2022 Meta ULC. All rights reserved