Mycobacterium tuberculosis miniepidemic in a church gospel choir

Chest
B T ManguraL B Reichman

Abstract

Conventional contact investigation and molecular fingerprinting of Mycobacterium tuberculosis isolates in tuberculosis (TB) outbreaks have facilitated recognition as well as application of public health control activities. Singing in a choir as an activity that promotes TB transmission has been occasionally recognized. Such avocational transmission in a middle class community can occur with attendant difficulties encountered in contact investigation. Five cases of TB (one index case; three secondary cases; one unassociated case) were identified among members of a famous church gospel choir in Newark, NJ. DNA fingerprinting and susceptibility testing were done on all retrieved strains. Of 306 choir members who had tuberculin tests, 19% were reactors. The presumed outbreak site was investigated. Four of the five patients were tenors, and one was an alto. Tenors were approximately twice as likely to be tuberculin reactors than subjects with other vocal ranges combined (relative risk, 2.04; 95% confidence interval, 1.17 to 3.56). An air ventilation outlet was directly in front of the tenor section. Some limited extra-church activity between choir members may have contributed to transmission. Conventional contact investigation must ...Continue Reading

References

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Citations

Oct 27, 2005·American Journal of Respiratory and Critical Care Medicine·UNKNOWN American Thoracic SocietyUNKNOWN Infectious Diseases Society of America
Feb 19, 2011·American Journal of Public Health·James R HargreavesJohn D H Porter
May 16, 2000·Chest·M Lauzardo, D Ashkin
Apr 5, 2014·Journal of Clinical Epidemiology·Chris CooperGillian M Craig
Apr 22, 2004·Internal Medicine·Yoichi NakamuraShigeru Kohno
Sep 3, 2011·Public Health Reports·Sara A LowtherRuth Lynfield
Nov 17, 2020·American Journal of Respiratory and Critical Care Medicine·Emily A KendallDavid W Dowdy

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