PMID: 29756729May 15, 2018Paper

Mycobacterium tuberculosis PhoP system

Wei sheng wu xue bao = Acta microbiologica Sinica
Yuan Zhang, Jianping Xie

Abstract

PhoPR is an important two-component regulatory system in Mycobacterium tuberculosis. PhoP is essential for virulence as a response regulator involved in cell wall lipid biosynthesis and regulation of gene expression. In this review, the structure, function and vaccine application of PhoP were summarized, as well as some questions that need to be solved.

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