PMID: 25793076Mar 21, 2015Paper

Mycoplasma pneumoniae infection with neurologic complications

Iranian Journal of Pediatrics
Sevgi YimenicioğluEner Cagrı Dinleyici

Abstract

Extrapulmonary complications of Mycoplasma pneumoniae (M. pneumoniae) infection include encephalitis, optic neuritis, acute psychosis, stroke, cranial nerve palsies, aseptic meningitis and also it may be implicated in immune mediated neurological diseases such as acute demyelinating encephalomyelitis, Guillain-Barre syndrome and transverse myelitis. We present five cases with acute neurological diseases after M. pneumoniae infection. The clinical presentations were characterized by encephalitis in 2 patients, Gullain-Barre syndrome in 2 patients, transverse myelitis in 1 patient. M. pneumoniae infection was detected in serum by serological method. Only two patients had respiratory symptoms preceding M. pneumoniae infection. Brain MRI revealed hyperintensities on corpus striatum and mesencephalon in one patient with encephalitis, the other had front parietal coalescent periventricular white matter lesions on T2 images. The patient with transverse myelitis had cervical, dorsal and lumbar scattered hyperintense lesions on T2 images. Two patients were treated with high dose steroid, the other two patients received treatment with intravenous immune globuline. M. pneumoniae may reveal different neurologic complications with different...Continue Reading

References

Oct 19, 2004·Clinical Microbiology Reviews·Ken B Waites, Deborah F Talkington
Aug 16, 2005·The Journal of Laboratory and Clinical Medicine·Randeep GuleriaNihar Ranjan Biswas
Sep 27, 2005·The Journal of Infection·S TsiodrasH Giamarellou
Aug 3, 2007·Pediatrics·Laura J ChristieCarol A Glaser

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