Mycotic Infections of the Eye

Advances in Clinical and Experimental Medicine : Official Organ Wroclaw Medical University
Mirosław SłowikMarta Misiuk-Hojło

Abstract

Fungal infections of the eye are an important cause of significant visual loss and blindness in some regions of the world, especially developing countries. Ocular mycoses remain a diagnostic and therapeutic challenge to the ophthalmologist. Corneal infection is the most frequent presentation, but the orbit, eyelids, lacrimal apparatus, conjunctiva, sclera and internal structures of the eye can also be affected. Candida spp., Fusarium spp. and Aspergillus spp. are the most frequently isolated organisms in fungal keratitis and in endophthalmitis. The difficulties posed by ocular mycoses are mainly related to establishing the clinical diagnosis, isolation of the fungal pathogen and effective local treatment, particularly in infections of the cornea. The critical issue in diagnosing fungal infection of the eye is microbiological identification of the etiologic agent in clinical samples. Early diagnosis and prompt treatment allow serious complications, including blindness, to be avoided. Local, systemic and even surgical treatment is applied in the therapy.

Citations

Oct 4, 2016·International Immunopharmacology·Xinran GaoGuoqiang Zhu
May 5, 2016·Drug Development and Industrial Pharmacy·Rakesh Kumar, Vivek Ranjan Sinha
Nov 21, 2017·F1000Research·Anna SkiadaMaria Drogari-Apiranthitou
Feb 7, 2018·Scientific Reports·Hyun Jung ParkChan Hum Park
Aug 29, 2020·Translational Vision Science & Technology·Giuseppe CelenzaPierangelo Bellio
Sep 14, 2021·Frontiers in Cellular and Infection Microbiology·Kazem AhmadikiaShahram Mahmoudi

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