Myelin Oligodendrocyte Glycoprotein-IgG-positive Recurrent Bilateral Optic Papillitis with Serous Retinal Detachment

Internal Medicine
Tomoya KonMasahiko Tomiyama

Abstract

Autoantibodies against myelin oligodendrocyte glycoprotein (MOG-IgG) have been detected in inflammatory demyelinating central nervous system diseases. A 30-year-old woman had blurred vision, marked optic nerve disc swelling, serous retinal detachment at the macular on optic coherence tomography, and MOG-IgG seropositivity. The patient was thought to have optic papillitis associated with MOG-IgG. Her symptoms rapidly improved after high-dose methylprednisolone therapy. We hypothesize that serous retinal detachment was secondary, arising from optic papillitis. This is the first report of the concurrence of optic papillitis with MOG-IgG and serous retinal detachment. MOG-IgG should be tested in patients with marked optic disc swelling.

References

Jan 1, 1987·Neuroradiology·G JohnsonW I McDonald
Nov 1, 1984·American Journal of Clinical Pathology·M C BeneJ Duheille
Nov 1, 1996·Neuroradiology·A GassD H Miller
Sep 27, 2001·Archives of Ophthalmology·V PurvinD M Jacobson
Jan 25, 2003·The British Journal of Ophthalmology·H E KillerJ Flammer
Jan 15, 2014·Neurology·Douglas Kazutoshi SatoKazuo Fujihara
Jan 31, 2015·Neurology. Neuroimmunology and Neuroinflammation·Scott S Zamvil, Anthony J Slavin
Oct 31, 2015·Neurology. Neuroimmunology and Neuroinflammation·Sung-Min KimPatrick Waters
Dec 29, 2015·Autoimmunity Reviews·Sudarshini RamanathanFabienne Brilot
Jan 13, 2016·Current Neurology and Neuroscience Reports·Simon J Hickman
Apr 30, 2017·American Journal of Ophthalmology·Mikee LiuganMing Zhang
May 17, 2017·Survey of Ophthalmology·Radgonde AmerNilüfer Yalçındağ

❮ Previous
Next ❯

Citations


❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift für Augenheilkunde
L REGENBOGENM LAZAR
Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie
Antonio FeaFederico Grignolo
Clinical Ophthalmology
Ana Marina SuelvesManuel Díaz-Llopis
The British Journal of Ophthalmology
Enken GundlachAmelie Pielen
© 2022 Meta ULC. All rights reserved