Myelodysplastic Syndrome Developing Presacral Extramedullary Hematopoiesis with Atypical MRI Findings

Internal Medicine
Haruki SawadaSadamu Okada

Abstract

A 64-year-old woman was diagnosed to have refractory cytopenia with multilineage dysplasia (RCMD) including an increased number of sideroblasts in the bone marrow (BM). Computed tomography (CT) revealed a presacral mass which showed iso- or high-intensity signals according to T1-weighted and hypo-intensity signals on T2-weighted magnetic resonance imaging (MRI). CT-guided biopsy revealed the presence of hematopoietic tissue with features that correlated with the BM findings. While the formation of extramedullary hematopoiesis in the presacral area is rare, it is important to differentiate it from other parasacral tumors even though such differentiation is often difficult. This patient demonstrated atypical MRI signals possibly due to an increase in the cellular iron content of the erythroid precursors.

References

May 27, 2004·Abdominal Imaging·A SingerM Z Simmons
Jul 18, 2006·Journal of the American Academy of Dermatology·Muzlifah A HaniffaNick B Simpson
Feb 23, 2007·The Surgeon : Journal of the Royal Colleges of Surgeons of Edinburgh and Ireland·J GhoshA J M Watson
Nov 22, 2011·Skeletal Radiology·Andrew W GinzelMark D Murphey
Feb 10, 2012·Journal of Gastrointestinal Cancer·Vassilios VassiliouDimitrios Andreopoulos
Jun 26, 2012·Clinical Imaging·Yasemin Işık BalcıMustafa Serdar Ateşçi
Oct 10, 2012·Journal of Medical Imaging and Radiation Oncology·Dharamraj SohawonDonald K Bowden
Feb 21, 2013·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Francesco BuccisanoAdriano Venditti
Aug 16, 2013·Histopathology·Carmen Martinez-LosadaJoaquin Sanchez-Garcia
Oct 22, 2013·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·Mohamed MackiAli Bydon
Dec 19, 2013·Iranian Journal of Radiology : a Quarterly Journal Published by the Iranian Radiological Society·Kaleem AhmadShatdal Chaudhary
Jun 16, 2014·Seminars in Ultrasound, CT, and MR·Eleni Orphanidou-VlachouChristos S Georgiades

❮ Previous
Next ❯

Citations


❮ Previous
Next ❯

Methods Mentioned

BETA
MDS
biopsy
with

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

JPMA. the Journal of the Pakistan Medical Association
M N AhmadZ Tasneem
Turkish Journal of Haematology : Official Journal of Turkish Society of Haematology
Semra PaydaşGülfiliz Gönlüşen
© 2022 Meta ULC. All rights reserved