Myelodysplastic syndrome presenting with clonal rearrangement isolated to chromosomal region 1q

Cancer Genetics and Cytogenetics
M J MogulP G Beatty

Abstract

Myelodysplastic syndrome (MDS) is a malignant hematologic disorder that may present with clinical features consistent with the diagnosis of severe aplastic anemia (SAA). Distinguishing the two disorders may depend on the presence of a clonal chromosomal abnormality. In the following, we report a case of MDS associated with what we believe to be a previously unreported clonal abnormality of chromosome 1q, a finding that enabled us to distinguish between MDS and SAA.

References

Jun 1, 1990·Cancer Genetics and Cytogenetics·M Jotterand-BellomoP Beris
Oct 15, 1993·Cancer Genetics and Cytogenetics·S SinghP Vincent

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