Myelodysplastic syndrome with neutrophilic panniculitis: A report of two cases and a literature review

Oncology Letters
Liren QianYuanyuan Ma

Abstract

Myelodysplastic syndrome (MDS) associated with neutrophilic panniculitis (NP) is rare. To the best of our knowledge, there are only five previously reported cases of MDS associated with NP, consisting of four adults and a young male. The present study reviews the literature of the previously reported cases and presents two case reports of adult male patients who were initially diagnosed as MDS. The two patients presented with a sudden onset of fever without infection and erythematous indurated papules. The patients were diagnosed with NP by skin biopsy and their symptoms disappeared completely following treatment with systemic corticosteroids. NP may be an independent high-risk factor for MDS. However, due to the rarity of such cases, the exact pathogenesis of NP associated with MDS requires further investigation.

References

Sep 1, 1995·The British Journal of Dermatology·Y SuzukiH Shinkai
Jan 1, 1997·The British Journal of Dermatology·Y MatsumuraS Imamura
Mar 14, 2002·The Journal of Dermatology·Wataru NishieMichiyo Kanagawa
Jan 17, 2004·Journal of the American Academy of Dermatology·Claudine Sutra-LoubetDaniel Wallach
May 8, 2009·Pediatric Dermatology·Guy HendrickxLinda De Raeve
Aug 14, 2009·Journal of Cutaneous Pathology·Kathryn BechererCharles Caldwell

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Methods Mentioned

BETA
MDS
biopsy
ESR

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