Myelofibrosis in children with chronic renal insufficiency.

The Journal of Pediatrics
N SchlackmanJ L Naiman

Abstract

During investigation of splenomegaly in a boy with chronic renal failure and osteodystrophy, bone marrow aspirates resulted in "dry taps," whereas biopsied material provided evidence that the marrow had been replaced by fibrous tissue. In a study of six other children with chronic renal failure, similar changes were observed. These findings suggest that the anemia of chronic renal failure may in part be a result of myelofibrosis, and the resulting reduction of functional bone marrow may limit the tolerance to immunosuppressive agents in patients who undergo renal transplantation.

References

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Citations

Feb 1, 1989·The Journal of Pediatrics·S YetginF Sarialioğlu
Oct 22, 2014·Indian Journal of Hematology & Blood Transfusion : an Official Journal of Indian Society of Hematology and Blood Transfusion·Annapurna SaksenaTejinder Singh
Feb 1, 1979·The Journal of Pediatrics·U Z Nordan, J R Humbert
Apr 1, 1981·The Journal of Pediatrics·S O LauJ H Kersey
Dec 1, 1982·European Journal of Pediatrics·D F GearyG A Richard
Feb 1, 1982·American Journal of Hematology·T J ConnellyR Silver
Feb 1, 1982·Scandinavian Journal of Haematology·S Yetgin, S Ozsoylu

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