Myobloc

Dermatologic Clinics
Timothy Corcoran Flynn

Abstract

Myobloc is the currently available commercial formulation of type B botulinum toxin. Released in the United States in 2000, it is approved by the Food and Drug Administration for the treatment of cervical dystonia. The most commonly used botulinum toxins, the type A toxins (Botox and Dysport), affect the SNAP-25 protein, whereas the type B toxin (Myobloc) affects vesicle-associated membrane protein, also known as synaptobrevin. Both type B and type A are antigenically distinct. This article explains the difference between Myobloc and type A toxins, reviews equivalency and other published studies, and describes practical uses for this product in facial aesthetics.

References

Jul 28, 2001·Seminars in Cutaneous Medicine and Surgery·J E CallawayA J Grethlein
Oct 16, 2001·Toxicon : Official Journal of the International Society on Toxinology·K R Aoki
Sep 25, 2002·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Neil S Sadick, Faacs

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Citations

Feb 14, 2009·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Timothy Corcoran Flynn
Jan 24, 2007·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Alastair CarruthersMichael S Leong
May 9, 2013·The Journal of Surgical Research·Dennis F SchweizerJan A Plock
Apr 9, 2008·Seminars in Cutaneous Medicine and Surgery·Timothy Corcoran Flynn
Jan 11, 2007·Survey of Ophthalmology·Jonathan J Dutton, Amy M Fowler
Oct 24, 2006·Seminars in Cutaneous Medicine and Surgery·Timothy Corcoran Flynn
Sep 11, 2007·Clinical Therapeutics·Mary Ann ChapmanP David Charles
Dec 5, 2009·International Journal of Oral and Maxillofacial Surgery·O W Majid

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Botulism is a rare but serious paralytic illness caused by a nerve toxin that is produced by the bacterium clostridium botulinum. Discover the latest research on botulism here.

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Botulism is a rare but serious paralytic illness caused by a nerve toxin that is produced by the bacterium clostridium botulinum. Discover the latest research on botulism here.

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