Myocardial deformation by strain echocardiography identifies patients with acute coronary syndrome and non-diagnostic ECG presenting in a chest pain unit: a prospective study of diagnostic accuracy

Clinical Research in Cardiology : Official Journal of the German Cardiac Society
Joerg SchroederMichael Becker

Abstract

Clinical assessment often cannot risk stratify patients hospitalized with chest pain and non-diagnostic electrocardiography (ECG) or myocardial enzymes. An inappropriate admission of patients with non-cardiac chest pain is an enormous cost factor. 2315 patients who presented in the chest pain unit (CPU) with symptoms suggestive of acute coronary syndrome (ACS) were screened. All patients with relevant changes in ECG or myocardial enzymes were excluded. 268 consecutive patients (mean 58 ± 7 years, 88 men) were prospectively included and underwent echocardiography for left ventricular ejection fraction (LVEF), wall motion score index (WMSI) and strain parameter and a coronary angiography (CA) within 2 ± 1 days after admission. Anatomically obstructive coronary artery disease (CAD) (≥70 % diameter stenosis) was present in 110 patients (41 %). The incremental value of LVEF, WMSI, and strain parameters to relevant clinical variables was determined in nested Cox models. Baseline clinical data associated with relevant CAD were age [hazard ratio (HR) 1.31, p = 0.03], arterial hypertension (HR 1.39, p = 0.03) and diabetes (HR 1.46, p = 0.001). The addition of endocardial global circumferential strain (GCS) (HR 1.57, p < 0.001) caused th...Continue Reading

Associated Clinical Trials

References

May 28, 2004·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Shimon A ReisnerZvi Friedman
Jul 12, 2005·International Journal of Cardiology·Gigliola BedettiEugenio Picano
Sep 1, 2005·Circulation·Jeane M TsutsuiThomas R Porter
Apr 4, 2006·Journal of the American College of Cardiology·W Patricia IngkanisornAndrew E Arai
Nov 9, 2007·European Heart Journal·Jeane M TsutsuiThomas R Porter
Apr 4, 2008·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Piotr LipiecJarosław D Kasprzak
Aug 5, 2008·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Ricardo C CuryJack A Ziffer
Jan 16, 2009·The New England Journal of Medicine·Pim A L ToninoUNKNOWN FAME Study Investigators
Apr 7, 2009·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Nicola GaibazziTiziano Gherli
Apr 30, 2009·European Journal of Echocardiography : the Journal of the Working Group on Echocardiography of the European Society of Cardiology·Jin-Oh ChoiSeung Woo Park
Feb 27, 2010·European Journal of Echocardiography : the Journal of the Working Group on Echocardiography of the European Society of Cardiology·Christian EekHelge Skulstad
Mar 28, 2012·The New England Journal of Medicine·Harold I LittJudd E Hollander
Sep 4, 2012·Journal of the American College of Cardiology·Marit Kristine SmedsrudThor Edvardsen

❮ Previous
Next ❯

Citations

Mar 24, 2017·Clinical Research in Cardiology : Official Journal of the German Cardiac Society·C EickAxel Bauer
Mar 31, 2018·Echocardiography·Antonello D'AndreaUNKNOWN Working Group on Echocardiography of the Italian Society of Cardiology
Apr 15, 2018·Clinical Research in Cardiology : Official Journal of the German Cardiac Society·Manli YuXinmiao Huang
May 20, 2018·Clinical Research in Cardiology : Official Journal of the German Cardiac Society·Maria Vincenza PolitoAndreas Hagendorff
Sep 25, 2019·Clinical Physiology and Functional Imaging·Rafik B ShenoudaMichael Y Henein
Oct 20, 2017·Cardiovascular Ultrasound·Wouter M van EverdingenMaarten J Cramer
Mar 13, 2019·Clinical Research in Cardiology : Official Journal of the German Cardiac Society·Ignatios IkonomidisEfstathios Iliodromitis
Mar 23, 2017·Clinical Research in Cardiology : Official Journal of the German Cardiac Society·Alexander SchuhMichael Becker
Jun 29, 2018·Clinical Research in Cardiology : Official Journal of the German Cardiac Society·Natig GassanovFikret Er
Aug 22, 2020·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·Ignatios IkonomidisEfstathios Iliodromitis
Apr 30, 2019·Current Problems in Cardiology·D MeleR Ferrari

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cardiomyopathy

Cardiomyopathy is a disease of the heart muscle, that can lead to muscular or electrical dysfunction of the heart. It is often an irreversible disease that is associated with a poor prognosis. There are different causes and classifications of cardiomyopathies. Here are the latest discoveries pertaining to this disease.