Myocardial deformation imaging based on ultrasonic pixel tracking to identify reversible myocardial dysfunction

Journal of the American College of Cardiology
Michael BeckerR Hoffmann

Abstract

This study evaluated the predictive value of myocardial deformation imaging for improvement in cardiac function after revascularization therapy in comparison with contrast-enhanced cardiac magnetic resonance imaging (ceMRI). Myocardial deformation imaging allows analysis of myocardial viability in ischemic left ventricular dysfunction. In 53 patients with ischemic left ventricular dysfunction, myocardial viability was assessed using pixel-tracking-derived myocardial deformation imaging and ceMRI to predict recovery of function at 9 +/- 2 months follow-up. For each left ventricular segment in a 16-segment model, peak systolic radial strain was determined from parasternal 2-dimensional echocardiographic views using an automatic frame-by-frame tracking system of natural acoustic echocardiographic markers (EchoPAC, GE Ultrasound, Horton, Norway), and the relative extent of hyperenhancement using ceMRI. Of 463 segments with abnormal baseline function, 227 showed regional recovery. Compared with segments showing functional improvement, those that failed to recover had lower peak radial strain (15.2 +/- 7.5% vs. 22.6 +/- 6.3%; p < 0.001) and a greater extent of hyperenhancement (56 +/- 29% vs. 14 +/- 17%; p < 0.001). Using a cutoff of...Continue Reading

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References

Apr 3, 1986·The New England Journal of Medicine·J TillischH Schelbert
Jan 1, 1997·AJR. American Journal of Roentgenology·N A Obuchowski
Jul 17, 1998·The New England Journal of Medicine·W WijnsP G Camici
Feb 3, 2007·Radiology·Elizabeth A SadowskiArjang Djamali
Apr 3, 2007·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Raymond Q MigrinoMing Zhao

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Citations

Oct 23, 2009·European Journal of Nuclear Medicine and Molecular Imaging·Giovanni Lucignani, Alberto Cuocolo
Mar 27, 2012·European Radiology·Dennis T L WongStephen G Worthley
Aug 30, 2008·Current Heart Failure Reports·James N Kirkpatrick, Roberto M Lang
Jul 6, 2012·European Heart Journal Cardiovascular Imaging·Victoria Delgado, Chin Tse Arnold Ng
Dec 18, 2010·European Heart Journal·Frank A FlachskampfWerner G Daniel
May 26, 2010·Journal of Cardiovascular Magnetic Resonance : Official Journal of the Society for Cardiovascular Magnetic Resonance·E Ryoung ChoiJae K Oh
Mar 22, 2014·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Christian RostFrank A Flachskampf
Oct 29, 2010·Cardiology Research and Practice·Kiyotake IshikawaMario J Garcia
Jun 29, 2012·The British Journal of Radiology·R P Steeds
Jan 11, 2012·The International Journal of Cardiovascular Imaging·Kiyotake IshikawaRoger J Hajjar
Jul 31, 2013·The Annals of Thoracic Surgery·Hironori MatsuhisaYutaka Okita
Sep 7, 2012·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Ertunc AltiokRainer Hoffmann
Oct 25, 2011·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Xiao Ju MaSheng Chen
Oct 5, 2010·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Fakhar Zaman KhanDavid Paul Dutka
Apr 7, 2010·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Holly GeyerPartho P Sengupta
Mar 18, 2009·Echocardiography·Gila Perk, Itzhak Kronzon
Sep 6, 2015·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Patrick MeimounJacques Boulanger
Apr 25, 2009·Journal of the American College of Cardiology·Arthur E Weyman
Jan 24, 2009·Journal of the American College of Cardiology·Anthony N DeMariaSotirios Tsimikas
Jun 13, 2009·JACC. Cardiovascular Imaging·Stephan AchenbachWilliam A Zoghbi
Dec 25, 2009·Expert Review of Cardiovascular Therapy·Caroline Cottrell, James N Kirkpatrick
Oct 18, 2012·Biomedical Papers of the Medical Faculty of the University Palacký, Olomouc, Czechoslovakia·Martin HutyraMilos Taborsky
Mar 10, 2010·Circulation·Christian MeyerPatrick Schauerte
Mar 17, 2011·Circulation. Cardiovascular Imaging·Brian D Hoit
Apr 5, 2014·Journal of the American Society of Nephrology : JASN·Rafael KramannGeorg Schlieper
Jun 11, 2015·Expert Review of Cardiovascular Therapy·Parash PokharelJonathan N Bella

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