PMID: 9637280Jun 24, 1998Paper

Myocardial glucose metabolism in patients with hypertrophic cardiomyopathy: assessment by F-18-FDG PET study

Annals of Nuclear Medicine
T UeharaT Nishimura

Abstract

In an investigation of myocardial metabolic abnormalities in hypertrophic myocardium, the myocardial glucose metabolism was evaluated with F-18-fluorodeoxyglucose (FDG) positron emission tomography (PET) in 32 patients with hypertrophic cardiomyopathy, and the results were compared with those in 9 patients with hypertensive heart disease. F-18-FDG PET study was performed in the fasting and glucose-loading states. The myocardial regional %dose uptake was calculated quantitatively. The average regional %dose uptake in the fasting state in the patients with asymmetric septal hypertrophy and dilated-phase hypertrophic cardiomyopathy was significantly higher than that in the patients with hypertensive heart disease (0.75 +/- 0.34%, 0.65 +/- 0.25%, and 0.43 +/- 0.22%/100 g myocardium, respectively). In contrast, the average %dose uptake in the glucose-loading state in the patients with asymmetric septal hypertrophy and dilated-phase hypertrophic cardiomyopathy was not significantly different from that in patients with hypertensive heart disease (1.17 +/- 0.49%, 0.80 +/- 0.44% and 0.99 +/- 0.45%, respectively). The patients with apical hypertrophy had also low %dose uptake in the fasting state (0.38 +/- 0.21%) as in the hypertensive h...Continue Reading

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Citations

Oct 16, 2008·Cardiovascular Research·Marc van BilsenGer J van der Vusse
Dec 17, 2015·Journal of Muscle Research and Cell Motility·Aldrin V GomesDanuta Szczesna-Cordary
Mar 15, 2003·European Journal of Nuclear Medicine and Molecular Imaging·Albert Flotats, Ignasi Carrió
Jan 30, 2013·Nuclear Medicine Communications·Min CaiZuo-Xiang He
Feb 6, 2019·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Takashi NorikaneYoshihiro Nishiyama
Aug 6, 2021·Radiology. Artificial Intelligence·Nicholas JosselynWalter R Witschey

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