PMID: 9538315Apr 16, 1998Paper

Myocardial infarction in young people with normal coronary arteries

Heart
M J WilliamsC J Low

Abstract

Myocardial infarction occurring in young people with angiographically normal coronary arteries is well described but the pathophysiology of this condition remains unknown. Coronary artery spasm in association with thrombus formation and minimal atheromatous disease or spontaneous coronary artery dissection are possible causes. Two young men presented with severe chest pain after acute alcohol intoxication and each sustained an extensive anterior myocardial infarction. Investigations including intravascular ultrasound showed no evidence of atherosclerotic coronary artery disease. Coronary artery spasm associated with acute alcohol intoxication as well as prothrombotic state and endothelial damage related to cigarette smoking may be mechanisms leading to acute myocardial infarction in these cases. Acute myocardial infarction occurs in young persons with normal coronary arteries and the diagnosis should be considered in young patients presenting with severe chest pain, particularly those abusing cocaine or alcohol, so that reperfusion therapy can be initiated promptly.

Citations

Apr 26, 2006·Circulation Journal : Official Journal of the Japanese Circulation Society·Jun ShiraishiUNKNOWN AMI-Kyoto Multi-Center Risk Study Group
Apr 6, 2007·The Journal of International Medical Research·I Biyik, O Ergene
Feb 1, 2019·International Journal of Molecular Sciences·Sung Tae Kim, Taehwan Park
Nov 26, 2005·Circulation Journal : Official Journal of the Japanese Circulation Society·Jun ShiraishiUNKNOWN AMI-Kyoto Multi-Center Risk Study Group
May 14, 2005·European Journal of Emergency Medicine : Official Journal of the European Society for Emergency Medicine·Ayman A El-MenyarJassim Al Suwaidi
Jul 7, 2015·Tobacco Induced Diseases·Rumana J KhanBruce N Leistikow
Jul 23, 2015·BMC Cardiovascular Disorders·Mohammad Azizul KarimSheikh Mohammed Shariful Islam
Mar 3, 2004·Circulation Journal : Official Journal of the Japanese Circulation Society·Hiroshi ImamuraKeishi Kubo
Aug 19, 2014·BioMed Research International·Xu JiaLina Chen
Aug 12, 1999·Alcoholism, Clinical and Experimental Research·G AddoloratoG Gasbarrini
Jan 11, 2003·American Journal of Therapeutics·Ramesh M GowdaTerrence J Sacchi
Aug 9, 2016·The American Journal of Forensic Medicine and Pathology·Xiulu RuanAlan David Kaye
Apr 6, 2007·Journal of Thrombosis and Haemostasis : JTH·V RoldánV Vicente
Jul 4, 2001·Academic Emergency Medicine : Official Journal of the Society for Academic Emergency Medicine·N J WalkerJ E Hollander
Aug 21, 2019·International Journal of Clinical Endocrinology and Metabolism·Mohammed Al-SadawiSamy I McFarlane

❮ Previous
Next ❯

Related Concepts

Related Feeds

Addiction

This feed focuses mechanisms underlying addiction and addictive behaviour including heroin and opium dependence, alcohol intoxication, gambling, and tobacco addiction.

Atherosclerosis Disease Progression

Atherosclerosis is the buildup of plaque on artery walls, causing stenosis which can eventually lead to clinically apparent cardiovascular disease. Find the latest research on atherosclerosis disease progression here.

Blood Clotting Disorders

Thrombophilia includes conditions with increased tendency for excessive blood clotting. Blood clotting occurs when the body has insufficient amounts of specialized proteins that make blood clot and stop bleeding. Here is the latest research on blood clotting disorders.