PMID: 15248452Jul 14, 2004Paper

Myocardial infarction revealing an antiphospholipid syndrome in a 27-year-old woman

Archives des maladies du coeur et des vaisseaux
Ph Y BaudouyJ Ch Piette

Abstract

We report the case of a 27 year old woman, with no vascular risk factors other than moderate smoking, admitted for a first acute anterior myocardial infarction. Emergency coronarography detected an isolated thrombosis, localised at the level of the middle section of the anterior inter-ventricular artery in an otherwise normal coronary network. Angioplasty of the artery with direct stenting was performed successfully and the follow up was uncomplicated. The diagnosis of primary antiphospholipid syndrome was made on the association of a raised level of anti-cardiolipin antibodies and the absence of elements in favour of an associated connective tissue disorder.

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Antiphospholipid Syndrome

Antiphospholipid syndrome or antiphospholipid antibody syndrome (APS or APLS), is an autoimmune, hypercoagulable state caused by the presence of antibodies directed against phospholipids.