Myocardial infarction with non-obstructive coronary arteries: what is the prognosis?

European Heart Journal Supplements : Journal of the European Society of Cardiology
Giampaolo Niccoli, Paolo G Camici

Abstract

Myocardial infarction in the absence of obstructive coronary stenosis (MINOCA) is a syndrome with several causes, characterized by clinical evidence of myocardial infarction and coronary angiographically normal or almost normal (stenosis ≤50%). MINOCAs represent about 10% of acute coronary syndromes. The causes of MINOCA are manifold and can be classified on the basis of the mechanism in epicardial (unstable plaque not manifested by angiography, epicardial spasm and coronary dissection) or microvascular. The latter in turn can be divided into intrinsic (microvascular spasm, Takotsubo syndrome and coronary embolization) and extrinsic (myocarditis). In the former, the dysfunctional microcirculation causes myocardial necrosis due to reduction of the lumen due to vasoconstriction and / or obstruction, while in the latter, the compression of the lumen occurs ab extrinsic due to myocardial edema. Note that the prognosis of MINOCA is extremely variable and depends on the underlying cause with high risk clinical subsets. A correct diagnostic procedure includes first level tests (clinical / anamnestic examination, ECG, myocardial necrosis enzyme dosage, trans-thoracic echocardiogram, coronary angiography, ventriculogram) and second leve...Continue Reading

References

Jun 27, 1998·Lancet·M MohriA Takeshita
Dec 21, 2014·European Heart Journal·Giampaolo NiccoliFilippo Crea
Jun 14, 2017·Circulation·Francesco PellicciaPaolo G Camici
May 17, 2018·Circulation·Enrico AmmiratiUNKNOWN Registro Lombardo delle Miocarditi
Nov 8, 2018·European Heart Journal·Kristian Thygesen

❮ Previous
Next ❯

Citations

Sep 10, 2020·Journal of Clinical Medicine·Federico VancheriMichael Henein
Jun 5, 2021·International Journal of Cardiology·Francesco PellicciaPaolo G Camici
May 29, 2021·World Journal of Transplantation·Anthony MattaJerome Roncalli
Jul 1, 2021·Interventional Cardiology·Robert SykesColin Berry
Jul 29, 2021·Arquivos brasileiros de cardiologia·José Carlos NicolauWilson Mathias Júnior
Dec 24, 2021·European Journal of Clinical Investigation·George Markousis-MavrogenisSophie I Mavrogeni

❮ Previous
Next ❯

Methods Mentioned

BETA
dissection
nuclear magnetic resonance

Software Mentioned

SWEDEHEART
ACUITY
VIRGO
MINOCA

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

European Heart Journal. Acute Cardiovascular Care
Giancarla ScaloneFilippo Crea
Giornale italiano di cardiologia : organo ufficiale della Federazione italiana di cardiologia : organo ufficiale della Società italiana di chirurgia cardiaca
Andrea BuonoEnrico Ammirati
Circulation Journal : Official Journal of the Japanese Circulation Society
Sivabaskari PasupathyJohn F Beltrame
© 2022 Meta ULC. All rights reserved