Myocardial injury and left ventricular performance after subarachnoid hemorrhage

Stroke; a Journal of Cerebral Circulation
S A MayerL M Klebanoff

Abstract

Electrocardiographic abnormalities and elevations of the creatine kinase myocardial isoenzyme (CK-MB) occur frequently after subarachnoid hemorrhage. In some patients, a reversible and presumably neurogenic form of left ventricular dysfunction is demonstrated by echocardiography. It is not known whether cardiac injury of this type adversely affects cardiovascular hemodynamic performance. We retrospectively studied 72 patients admitted to our neuro-ICU for aneurysmal subarachnoid hemorrhage over a 2.5-year period. We selected patients who met the following criteria: (1) CK-MB levels measured within 3 days of onset, (2) pulmonary artery catheter placed, (3) echocardiogram performed, and (4) no history of preexisting cardiac disease. Hemodynamic profiles were recorded on the day after surgery (n=67) or on the day of echocardiography (n=5) if surgery was not performed (mean, 3. 3+/-1.7 days after onset). The severity of cardiac injury was classified as none (peak CK-MB <1%, n=36), mild (peak CK-MB 1% to 2%, n=21), moderate (peak CK-MB >2%, n=6), or severe (abnormal left ventricular wall motion, n=9). Abnormal left ventricular wall motion occurred exclusively in patients with peak CK-MB levels >2% (P<0.0001), poor neurological grade...Continue Reading

References

Aug 1, 1977·Journal of Neurology, Neurosurgery, and Psychiatry·G FabinyiL McKinley
Jun 11, 1992·Italian Journal of Neurological Sciences·M SalvatiF Cosentino
Jul 1, 1991·Journal of Neurosurgery·M L Levy, S L Giannotta
Mar 1, 1990·Proceedings of the Society for Experimental Biology and Medicine·C F PilatiM B Maron
Sep 1, 1988·Journal of the American College of Cardiology·C PollickC Tator
May 1, 1986·Critical Care Medicine·S L NorrisM Grace
May 1, 1969·Journal of Neurosurgery·J H Greenhoot, D D Reichenbach
Mar 1, 1980·Journal of Neurosurgery·R Doshi, G Neil-Dwyer
Oct 1, 1994·International Journal of Cardiology·R J PintoS N Bhagwati
Jan 1, 1994·Acta neurochirurgica·C H RabbS L Giannotta
Sep 1, 1994·Journal of the American College of Cardiology·T KonoA Fujiwara
May 1, 1994·The American Journal of Emergency Medicine·B R Asplin, R D White
Jul 1, 1993·American Heart Journal·L R HandlinS K Rowe

❮ Previous
Next ❯

Citations

Sep 18, 2012·Neuroradiology·Francisco Brevis NuñezChristian Dohna-Schwake
Apr 7, 2006·Clinical Research in Cardiology : Official Journal of the German Cardiac Society·H GraweH P Kühl
Jul 9, 2008·Current Atherosclerosis Reports·William Gump, Daniel T Laskowitz
Nov 3, 2005·Current Neurology and Neuroscience Reports·Alexander GrunsfeldBarnett R Nathan
Mar 5, 2013·Current Treatment Options in Cardiovascular Medicine·Amit S Dande, Amrita S Pandit
Jul 20, 2011·Neurocritical Care·Peter D Le Roux, UNKNOWN Participants in the International Multi-disciplinary Consensus Conference on the Critical Care Management of Subarachnoid He
Jul 20, 2011·Neurocritical Care·Jonathan G ZaroffSteve Sidney
Jul 16, 2011·Neurocritical Care·Nicolas BruderUNKNOWN Participants in the International Multi-Disciplinary Consensus Conference on the Critical Care Management of Subarachnoid He
Feb 9, 2012·Neurocritical Care·Michael MoussouttasKarel Pacak
May 12, 2012·Neurocritical Care·Antoine BaumannGérard Audibert
Jul 31, 2013·Neurocritical Care·Katharina M BuslRichard E Temes
May 12, 2005·Annales Françaises D'anesthèsie Et De Rèanimation·P HansH Dufour
Jun 15, 2004·International Journal of Cardiology·Tsung O Cheng
Dec 24, 2003·Journal of Critical Care·David A ZygunDavid K Menon
Aug 15, 2002·Toxicon : Official Journal of the International Society on Toxinology·Palmira Cupo, Sylvia Evelyn Hering
Mar 15, 2001·Surgical Neurology·J W Donaldson, M B Pritz
Aug 22, 2003·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Jonathan BirnsRoxy Senior
Apr 11, 2002·Acta Anaesthesiologica Scandinavica·G LambertP Friberg
May 29, 2002·Clinical Endocrinology·Eric A EspinerA Mark Richards
Feb 11, 2005·The New England Journal of Medicine·Ilan S WittsteinHunter C Champion
Apr 20, 2004·Critical Care Medicine·Jan ClaassenStephan A Mayer
Dec 24, 2005·Critical Care Medicine·Jeremy M KahnGordon D Rubenfeld
Jun 2, 2006·Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies·Myke DrayerRick Harrison
Aug 1, 2012·Gastroenterology Nursing : the Official Journal of the Society of Gastroenterology Nurses and Associates·LiYa HuangShaoQi Yang
Jan 12, 2008·The Journal of Trauma·Ali SalimDemetrios Demetriades
Nov 21, 2008·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Ameya NayateWilliam T Talman
Jan 12, 2010·Cases Journal·Marcello MarcìNicola Sanfilippo
Mar 21, 2012·Critical Care : the Official Journal of the Critical Care Forum·Danielle L DavisonLakhmir S Chawla
Feb 1, 2011·Continuum : Lifelong Learning in Neurology·Bassel Raad, Cathy Sila
Jul 1, 2005·Neurosurgery·L Gerard ToussaintJohn L D Atkinson
Sep 19, 2008·Journal of Cardiovascular Medicine·Emanuele Catena, Donato Mele
May 4, 2010·Journal of Neurosurgery. Pediatrics·Jeremiah JohnsonSanjiv Bhatia
Jul 12, 2012·Journal of Geriatric Cardiology : JGC·Michael A Chen
Jan 10, 2008·Annals of Cardiac Anaesthesia·Feyzi ArtukogluThomas M Hemmerling

❮ Previous
Next ❯

Related Concepts

Related Feeds

Blood Clotting Disorders

Thrombophilia includes conditions with increased tendency for excessive blood clotting. Blood clotting occurs when the body has insufficient amounts of specialized proteins that make blood clot and stop bleeding. Here is the latest research on blood clotting disorders.

Brain Ischemia

Brain ischemia is a condition in which there is insufficient blood flow to the brain to meet metabolic demand. Discover the latest research on brain ischemia here.

Cardiomyopathy

Cardiomyopathy is a disease of the heart muscle, that can lead to muscular or electrical dysfunction of the heart. It is often an irreversible disease that is associated with a poor prognosis. There are different causes and classifications of cardiomyopathies. Here are the latest discoveries pertaining to this disease.