Myocardial insult and arrhythmias after acute hemorrhage in horses

Journal of Veterinary Emergency and Critical Care
Cristobal Navas de SolisJoAnn Slack

Abstract

The objectives of this investigation were to: (1) Determine if acute hemorrhage is associated with increased plasma cardiac troponin I (cTnI) concentration or cardiac arrhythmias, (2) to describe the types of arrhythmias and their clinical course in horses following acute hemorrhage, (3) to determine the ability of clinical or clinicopathological variables to predict an increase in cTnI concentration and the presence of arrhythmias, and (4) to determine the associations of cTnI and cardiac arrhythmias with outcome. Prospective observational study. Large animal veterinary teaching hospital. Eleven client-owned adult horses admitted for treatment of acute hemorrhage (HG) and 4 adult horses undergoing controlled blood collection (BDG). Serial cTnI concentrations were measured and continuous ECGs were obtained from the HG and BDG groups. Statistical tests were used to determine associations among acute hemorrhage and plasma cTnI concentrations, the presence of cardiac arrhythmias, clinicopathologic data (heart rate [HR], packed cell volume [PCV], total plasma protein [TPP], plasma lactate, and plasma creatinine concentrations), and outcome. Plasma cTnI concentration and ECG were within reference intervals at all time points in the ...Continue Reading

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Citations

Dec 17, 2021·Journal of Veterinary Pharmacology and Therapeutics·Daniela LuethyJoann Slack

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