PMID: 9420680Mar 1, 1994Paper

Myocardial single-photon emission computed tomographic imaging with technetium 99m tetrofosmin: stress-rest imaging with same-day and separate-day rest imaging

Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology
B SridharaA Lahiri

Abstract

Technetium 99m tetrofosmin is a new ethylene diphosphine ligand for myocardial perfusion imaging and has unique properties. We have compared stress-rest single-photon emission computed tomographic (SPECT) imaging with 99mTc tetrofosmin with same-day and separate-day rest imaging to detect myocardial perfusion defects. Myocardial SPECT imaging was performed in 22 patients with coronary artery disease who had undergone planar thallium 201 imaging and coronary angiography. Single-day (stress-rest) and separate-day rest 99mTc tetrofosmin SPECT protocols were compared in the same patient. Images were assessed by a blinded panel to identify myocardial infarction, ischemia, or normal scans. Overall sensitivity for identification of patients with coronary artery disease was 86% (19/22) by both same-day stress-rest and separate-day rest protocols with 99mTc tetrofosmin (p = NS). Of a total of 396 segments studied, 107 abnormal segments were identified at exercise and 76 and 81 at the same-day and separate-day rest tests, respectively (p = NS). Same-day stress-rest and separate-day rest 99mTc tetrofosmin SPECT protocols were also useful for detecting individual coronary stenosis with a greater than 50% lesion: 80% of the left anterior de...Continue Reading

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Citations

Jun 1, 1996·International Journal of Cardiac Imaging·M PillayS Mathews
Mar 14, 2003·European Journal of Nuclear Medicine and Molecular Imaging·Seishi NakamuraToshiji Iwasaka
Jul 1, 1995·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·R SeniorA Lahiri
Jul 1, 1997·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·R S KhattarA Lahiri
Jun 29, 1999·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·E NicolaiM Salvatore
Mar 16, 2000·Nuclear Medicine Communications·M SpadaforaP Miletto

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