Myocardial viability assessment with gated SPECT Tc-99m tetrofosmin % wall thickening: comparison with F-18 FDG-PET

Annals of Nuclear Medicine
Atsushi MaruyamaTsunehiko Nishimura

Abstract

This study was designed to assess the value of gated SPECT Tc-99m-tetrofosmin (TF) wall thickening (WT) in addition to TF exercise (Ex)/rest myocardial SPECT, in comparison with F-18 fluorodeoxyglucose (FDG)-PET. The study population consisted of 33 patients with old myocardial infarction (27 men and 6 women; mean age, 62 +/- 8 years old). All patients underwent Ex/rest TF SPECT and glucose loading FDG-PET. Polar map images of Ex/rest TF were generated and divided into 24 segments for further analysis. We classified LV segments according to the exercise-rest perfusion scintigraphy. LV segments with less than 70% of the maximum TF activity on the exercise image were defined as stress-induced defects. Among these, the segments whose TF activity increased by 10% from exercise to rest images or exceeded 70% of the maximum uptake were defined as reversible (viable) defects. The remaining defects on the rest image were irreversible (non-viable) defect segments, and were considered for viability study on the basis of %WT. %WT was calculated according to the standard method: [(counts ES - counts ED)/counts ED] x 100. A viable segment on gated SPECT was defined as a segment whose %WT exceeded the lower limit of the normal value (mean - ...Continue Reading

References

Jun 1, 1979·Journal of Computer Assisted Tomography·E J HoffmanM E Phelps
May 1, 1979·Medical Instrumentation·E J Hoffman, M E Phelps
Oct 1, 1991·Journal of the American College of Cardiology·C A NienaberM E Phelps
Sep 1, 1988·Circulation·H R Schelbert, D Buxton
Apr 3, 1986·The New England Journal of Medicine·J TillischH Schelbert
Jan 1, 1994·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·N TakahashiJ Konishi
May 1, 1995·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·K A Williams, L A Taillon
Mar 4, 2000·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·A CuocoloM Salvatore

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Citations

Mar 7, 2020·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Pavithra S Jayadeva, Nathan Better
Feb 16, 2020·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Feifei ZhangYuetao Wang

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