Myocarditis in dogs: etiology, clinical and histopathological features (11 cases: 2007-2013)

Irish Veterinary Journal
Izabela JanusKarolina Jabłońska

Abstract

Myocarditis is a disease caused by numerous etiological factors and characterized by a non-specific course. The only method allowing for precise characterization of inflammatory changes is the histopathological examination of heart muscle specimens. The study was conducted on heart muscle preparations from 11 dogs with ante-mortem diagnosis of cardiac disease. Animals presented with a poor response to an applied treatment or had suspected sudden cardiac death. The heart specimens were taken post-mortem, preserved and stained with haematoxylin and eosin. Subsequently, the presence and intensity of changes, i.e. inflammatory infiltration, the amount of connective tissue and features of cardiomyocyte degeneration were estimated. The specimens from dogs suspected of having a myocarditis of bacteriological etiology underwent additional bacteriological and immunohistochemical examination. The examination revealed an inflammatory infiltration of variable intensity combined with the degenerative changes in all dogs. There were vegetative and abnormal cystic forms of Borrelia burgdorferi sensu lato in 6 dogs. A Staphylococcus aureus infection was confirmed in one dog and an acute coronary syndrome with neutrophil infiltration was reveal...Continue Reading

References

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Citations

May 4, 2016·Microbes and Infection·Leena MeriläinenLeona Gilbert
Jul 15, 2016·BioMed Research International·Alessandro CostagliolaOrlando Paciello
Jun 14, 2017·Journal of Veterinary Internal Medicine·M TropfH Y Weng
Jan 18, 2020·JFMS Open Reports·Camilla Tørnqvist-JohnsenDanièlle A Gunn-Moore
Jun 17, 2020·Journal of Animal Science·Sydney R McCauleyEva M Oxford
Jul 18, 2020·Frontiers in Veterinary Science·Alessandra GavazzaMatteo Cerquetella
Apr 4, 2017·Journal of Veterinary Research·Agnieszka Noszczyk-NowakUrszula Pasławska

Methods Mentioned

BETA
biopsy
biopsies

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