PMID: 7520413Jun 1, 1994Paper

Myoepithelial carcinoma of the breast with distant metastasis and accompanied by adenomyoepitheliomas

Histopathology
P C ChenR B Wait

Abstract

A breast tumour in a 47-year-old female with axillary lymph node metastasis was interpreted as the rare malignant adenomyoepithelioma based on morphological and immunohistochemical studies. Multiple bone metastases developed and the patient died after 7 months. The malignant neoplasm consisted of cords and interlacing bundles of spindle cells with indistinct cell borders and clear cytoplasm. The cells stained positively for cytokeratin, S-100 protein, GFAP, and muscle-specific actin, and possessed basal lamina, pinocytic vesicles, tonofilaments, desmosomes, and intermediate filaments with dense bodies. In some areas, cells with microvillous projections enclosed small spaces. In the breast, foci of myoepithelioma with various morphological subtypes and infiltration coexisted, demonstrating the origin of the malignant tumour. The histogenesis of the myoepithelial tumours is discussed.

References

Sep 1, 1992·The American Journal of Surgical Pathology·J H LooseS M Katz
Oct 1, 1990·The American Journal of Surgical Pathology·C A MoranD Carter
Jun 1, 1991·The American Journal of Surgical Pathology·F A Tavassoli
Feb 1, 1991·The American Journal of Surgical Pathology·L R BéginS Frenkiel
Nov 1, 1985·Proceedings of the National Academy of Sciences of the United States of America·S H DairkeeA J Hackett
Jul 6, 1988·Journal of the National Cancer Institute·S H DairkeeA J Hackett
Dec 1, 1987·Human Pathology·P P Rosen
Mar 1, 1988·American Journal of Clinical Pathology·R H Young, P B Clement
Jan 1, 1985·Ultrastructural Pathology·I Dardick
Oct 1, 1974·The Journal of Pathology·H M CameronW Warambo
Dec 1, 1982·The American Journal of Surgical Pathology·R A Erlandson, P P Rosen

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Citations

Mar 29, 1996·Breast Cancer : the Journal of the Japanese Breast Cancer Society·Y ParkM Yanagida
Jan 1, 2010·Cancers·Jennifer R Choo, Torsten O Nielsen
May 20, 1998·The American Journal of Surgical Pathology·R H SimpsonM Michal
Jan 6, 2001·Brain Pathology·W MuellerA von Deimling
Nov 7, 2001·Pathology International·M HayashiT Motoyama
Apr 6, 2013·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·Werner BoeckerIgor Buchwalow
May 1, 2018·The Journal of Pathology·Stephan BartelsHans Kreipe
Oct 6, 2006·Journal of Neuropathology and Experimental Neurology·Mark W BecherLarry E Davis
Mar 17, 2015·The Breast Journal·Nasrollah AhmadiYahya Daneshbod
Nov 8, 2007·Breast Cancer : the Journal of the Japanese Breast Cancer Society·Hajime HikinoHiroshi Miura
Feb 2, 2008·Surgery Today·Toshiro YaharaTeruhiko Fujii
Mar 6, 2009·Pathology International·Yumi Honda, Ken-ichi Iyama
Jun 26, 1999·Histopathology·P HinzeD Katenkamp
Nov 25, 2000·Breast Cancer : the Journal of the Japanese Breast Cancer Society·I TakahashiI Yamamoto
Jan 25, 2011·Pathology International·Tadashi Terada
Sep 5, 2006·Archives of Pathology & Laboratory Medicine·Celina M NadelmanMichael C Fishbein
Dec 3, 2004·ANZ Journal of Surgery·Ross R JennensMichael Gonzales
Dec 26, 2003·Seminars in Diagnostic Pathology·Audrey K BennettMark R Wick
Nov 1, 2013·World Journal of Surgical Oncology·Vincenzo PetrozzaCarlo Della Rocca

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