PMID: 1197893Jan 1, 1975Paper

Myofibrillar alterations in ischemic myocardium after glucose-insulin-potassium infusion

Recent Advances in Studies on Cardiac Structure and Metabolism
H D Sybers, M Ashraf

Abstract

GIK infusion after experimental coronary artery ligation in dogs appears to reduce the size of the infarct and influence the ultrastructure of some of the cells bordering the infarct. These cells contain fine filamentous material thought to be actin, which appears to originate near the intercalated disc and is thought to represent a reparative process in reversibly injured cells and a hypertrophic response in normal cells adjacent to the infarct.

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