Myofibroblasts in oral potentially malignant disorders: Is it related to malignant transformation?

Oral Diseases
R D Coletta, T Salo

Abstract

In oral cancer, acquisition of α-smooth muscle actin (α-SMA)-positive fibroblasts, known as myofibroblasts or carcinoma-associated fibroblasts (CAF), is an important event for progression and metastasis. However, the contribution of myofibroblasts in oral potentially malignant disorders (OPMD) remains controversial. This systematic review provides evidence that immunodetection of myofibroblasts may identify oral submucous fibrosis (OSMF) with high risk of malignant transformation, but does not represent an auxiliary tool to predict the malignant potential of leukoplakia and erythroplakia, the most common OPMD.

References

Jun 16, 2004·Oral Diseases·A MarkopoulosI Kayavis
Apr 4, 2007·Journal of Clinical Periodontology·Lays M SobralRicardo D Coletta
May 9, 2009·Cancer Microenvironment : Official Journal of the International Cancer Microenvironment Society·Marilena VeredDan Dayan
May 29, 2009·Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology·S Etemad-MoghadamM Alaeddini
Jan 5, 2011·Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology·Punnya V AngadiSeema Hallikerimath
Feb 3, 2012·Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology·Nobuyuki FujiiHisao Ito
Feb 11, 2012·Medicina oral, patología oral y cirugía bucal·Eliene-Magda de-AssisMartinho-Campolina-Rebello Horta
Dec 18, 2013·Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology·Rui LuGang Zhou
Jan 10, 2014·Journal of Cellular and Molecular Medicine·Yu-Chao ChangWen-Wei Chang
Sep 16, 2014·International Journal of Cancer. Journal International Du Cancer·Jacques FerlayFreddie Bray
Jan 27, 2015·Oncology Letters·Priscila Campioni RodriguesRicardo D Coletta
Oct 5, 2016·Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology·Himalaya ParajuliDaniela Elena Costea
Oct 18, 2016·Journal of the Mechanical Behavior of Biomedical Materials·Anji AnuraJyotirmoy Chatterjee

❮ Previous
Next ❯

Citations

Jan 9, 2020·JBI Database of Systematic Reviews and Implementation Reports·Fernanda Weber MelloElena Riet Correa Rivero
Jul 16, 2020·Brazilian Dental Journal·Francisco Jadson LimaÉricka Janine Dantas da Silveira
Aug 20, 2020·JBI Evidence Synthesis·Fernanda Weber MelloElena Riet Correa Rivero
Feb 20, 2019·Journal of Cellular Physiology·Junyi HuZhaohui Chen
Feb 20, 2019·International Journal of Molecular Sciences·Catarina Roma-RodriguesAlexandra R Fernandes

❮ Previous
Next ❯

Related Concepts

Related Feeds

Carcinoma, Squamous Cell

Basal cell carcinoma is a form of malignant skin cancer found on the head and neck regions and has low rates of metastasis. Discover the latest research on basal cell carcinoma here.

Related Papers

Czasopismo stomatologiczne
J GawlikD Samolczyk
Brazilian Journal of Otorhinolaryngology
Elaini Sickert HosniMaria Antonia Zancanaro Figueiredo
Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics
H Ephros, A Samit
© 2022 Meta ULC. All rights reserved