PMID: 9431509Feb 12, 1998Paper

Myogenic responses of isolated lymphatics: modulation by endothelium

Microcirculation : the Official Journal of the Microcirculatory Society, Inc
Risuke MizunoG Kaley

Abstract

To characterize the effect of increases of intraluminal pressure on the spontaneous diameter oscillations of isolated lymphatics and on the maximum and minimum diameter, in the presence and absence of endothelium. Afferent lymphatics were isolated from rat iliac lymph nodes. After cannulation of both ends, lymphatics were equilibrated for 60 minutes at a pressure of 6 cm H2O, and then changes in diameter oscillations to increases in perfusion pressure (from 2-10 cm H2O, were measured. The endothelium was removed by intraluminal infusion of air. Changes in diameter were expressed as a percentage of the corresponding passive diameter obtained in Ca(2+)-free solution. Isolated lymphatics showed phasic spontaneous constriction and dilation (approximately 50 to approximately 150 microns). Removal of extracellular Ca2+ abolished spontaneous diameter oscillations, and the passive diameter increased from 183.0 +/- 5.3 to 205.1 +/- 8.8 microns as pressure increased from 2 to 10 cm H2O. In response to increases in pressure, the normalized minimum diameter (Dmin) increased (from 30.1% +/- 1.1% to 54.8% +/- 1.9% while the normalized maximum diameter (Dmax) of lymphatics did not change. With increasing pressure the amplitude of vasomotion (...Continue Reading

Citations

Sep 30, 2005·Lymphatic Research and Biology·Risuke MizunoToshio Ohhashi
Dec 14, 2006·The American Journal of Chinese Medicine·Michiaki YamakageAkiyoshi Namiki
Aug 12, 2009·American Journal of Physiology. Heart and Circulatory Physiology·H Glenn BohlenDave Zawieja
Sep 6, 2011·American Journal of Physiology. Heart and Circulatory Physiology·H Glenn BohlenDavid C Zawieja
Nov 26, 2008·American Journal of Physiology. Heart and Circulatory Physiology·Michael J DavisAnatoliy A Gashev
Nov 13, 2008·The Journal of Physiology·Michael J DavisAnatoliy A Gashev
Jun 4, 2008·Annals of the New York Academy of Sciences·Mariappan Muthuchamy, David Zawieja
Aug 24, 2012·Microcirculation : the Official Journal of the Microcirculatory Society, Inc·Koichiro KimizukaToshio Ohhashi
Sep 16, 2011·Basic & Clinical Pharmacology & Toxicology·Jens C B Jacobsen, Niels-Henrik Holstein-Rathlou
Jan 27, 2015·Seminars in Cell & Developmental Biology·Sanjukta ChakrabortyMariappan Muthuchamy
Jun 6, 2006·Biophysical Journal·Michèle KoenigsbergerJean-Jacques Meister
Oct 21, 2016·PloS One·Viktoria HasselhofJörg Wilting
Aug 6, 2017·American Journal of Physiology. Heart and Circulatory Physiology·Andrea N TrujilloJerome W Breslin
Dec 19, 2017·Lymphatic Research and Biology·Scott D ZawiejaMichael J Davis
Aug 17, 2004·American Journal of Physiology. Heart and Circulatory Physiology·Akira KousaiToshio Ohhashi
Jun 21, 2005·American Journal of Physiology. Heart and Circulatory Physiology·Nobuyuki OnoToshio Ohhashi
Jan 10, 2006·American Journal of Physiology. Heart and Circulatory Physiology·Anatoliy A GashevDavid C Zawieja
Apr 27, 2019·Physiological Reports·Anders L MoellerEbbe Boedtkjer
Dec 17, 2015·World Journal of Gastroenterology : WJG·Germaine D AgollahSunkuk Kwon
Mar 17, 2007·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Joshua K MeisnerChristopher M Quick
May 14, 2003·American Journal of Physiology. Heart and Circulatory Physiology·Kayoko HosakaToshio Ohhashi
Apr 30, 2014·American Journal of Physiology. Heart and Circulatory Physiology·Niklas TeliniusDonna Briggs Boedtkjer
Oct 11, 2017·The Journal of Physiology·Erik J BehringerSteven S Segal
Apr 14, 2000·American Journal of Physiology. Gastrointestinal and Liver Physiology·Y ShirasawaT Ohhashi
Apr 3, 2007·American Journal of Physiology. Heart and Circulatory Physiology·Jerome W BreslinMack H Wu
Apr 5, 2020·Scientific Reports·Mohammad S RazaviRudolph L Gleason
Aug 30, 2003·American Journal of Physiology. Heart and Circulatory Physiology·Yuichi Shirasawa, Joseph N Benoit
Jun 19, 2001·American Journal of Physiology. Heart and Circulatory Physiology·R MizunoT Ohhashi
Apr 8, 1998·The American Journal of Physiology·R MizunoG Kaley

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