PMID: 1924913Jan 1, 1991Paper

Myoglobinuric acute renal failure following electrical injury

Renal Failure
K L GuptaK S Chugh

Abstract

Eight patients with acute renal failure (ARF) following electrical injury were studied. The mean area of cutaneous burns was 23 +/- 16% (range 6-60%) and extensive tissue necrosis with gangrene was uniformly present. Oliguria developed 9.3 +/- 7 h (range 3-24 h) after the injury in 7 patients (88%). Urinalysis revealed presence of myoglobin in 75% of the patients. The mean duration of oliguria among those who recovered was 16 +/- 6 days (range 11-23 days) and the mean interval between the onset of oliguria and recovery of renal function was 25 +/- 6 days (range 21-34 days). Four patients died. The cause of death was Klebsiella septicemia in 1, hyperkalemia associated with extensive myonecrosis in 2 patients, and uncertain in 1 patient. Our observations showed that myoglobinuric acute renal failure associated with electrical injury carries a high mortality. Early detection and aggressive management of hyperkalemia and sepsis are necessary to reduce mortality among these patients.

References

Jan 1, 1968·Scandinavian Journal of Plastic and Reconstructive Surgery·O B JepsenM Thomsen
Nov 1, 1974·American Journal of Surgery·C P Artz
Jan 1, 1984·Scandinavian Journal of Plastic and Reconstructive Surgery·G Arturson, A Hedlund

Citations

Apr 27, 1995·Forensic Science International : Synergy·K PüschelJ Bartel
Dec 22, 1999·Forensic Science International : Synergy·A FieguthW J Kleemann
Apr 12, 2001·The Journal of Emergency Medicine·M Sungur, M Güven
Sep 28, 1999·The Journal of Emergency Medicine·C L RosenR Sheridan
Oct 23, 2010·Burns : Journal of the International Society for Burn Injuries·Peter L StollwerckFrank Siemers
Apr 18, 2016·The American Journal of Emergency Medicine·Turkmen SuhaTuredi Süleyman
Sep 22, 1998·Anesthesiology·N MacLennanB F Cullen
May 3, 2019·The Journal of Trauma and Acute Care Surgery·Christopher J Andrews, Dorin Panescu

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