Myopia and cognitive dysfunction among elderly Chinese adults: a propensity score matching analysis

Ophthalmic & Physiological Optics : the Journal of the British College of Ophthalmic Opticians (Optometrists)
Hong-Peng SunChen-Wei Pan

Abstract

The association between myopia and cognitive dysfunction among elderly adults was assessed by applying a Propensity Score Matching (PSM) approach. This is a statistical method which allows investigators to estimate causal treatment effects using observational or nonrandomised data. The study was designed as a community-based cross-sectional study based on a Chinese cohort aged 60 years or older in China. Objective refraction was measured using an autorefractor and subjective refraction was used to refine vision, using the results of the objective refraction as the starting point. Myopia was defined as a spherical equivalent value of less than -0.50 dioptre (D) in the right eye. The Abbreviated Mental Test (AMT) was used for cognitive assessment. The propensity scores for myopia were formulated using 13 potential confounders. We matched the propensity scores for subjects with and without myopia within a caliper of 0.01 of logit function of propensity scores. About 4123 elderly adults who successfully completed the AMT were included in this analysis. The odds ratio (OR) of cognitive dysfunction for myopia before matching was 1.98 (95% confidence interval [CI] 1.61, 2.44; p < 0.001). There were significant covariate imbalances bet...Continue Reading

References

Aug 17, 2005·Ophthalmic & Physiological Optics : the Journal of the British College of Ophthalmic Opticians (Optometrists)·Seang-Mei SawWei-Han Chua
Dec 13, 2006·Archives of Ophthalmology·David B ReinJinan Saaddine
Mar 11, 2008·Investigative Ophthalmology & Visual Science·Robert van de BergPaul N Baird
Dec 6, 2008·American Journal of Ophthalmology·Hwee-Bee WongSeang-Mei Saw
Dec 14, 2011·Ophthalmic & Physiological Optics : the Journal of the British College of Ophthalmic Opticians (Optometrists)·Chen-Wei PanSeang-Mei Saw
May 9, 2012·Lancet·Ian G MorganSeang-Mei Saw
Jan 12, 2013·Investigative Ophthalmology & Visual Science·Shin-Yeu OngCarol Y Cheung
May 21, 2013·Geriatrics & Gerontology International·Leandro FerreiraJosé Carlos Fernandes Galduróz
Aug 14, 2013·American Journal of Ophthalmology·Chen-Wei PanTien Y Wong
Oct 26, 2013·Investigative Ophthalmology & Visual Science·Ying-Feng ZhengSeang-Mei Saw

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Citations

Aug 16, 2016·Optometry and Vision Science : Official Publication of the American Academy of Optometry·Haifang WangChen-Wei Pan

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