Myosin heavy chain isoforms in smooth muscle

Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology
E LoukianovM Periasamy

Abstract

In recent years, significant progress has been made toward understanding smooth muscle myosin heavy chain (SMHC) structure. Molecular cloning analysis has identified four different MHC isoforms. They are products of a single gene and result from alternative mRNA splicing. In addition, two non-muscle MHC isoforms are also expressed in smooth muscle cells. Studies show that SMHC expression is highly tissue specific and does not appear in cardiac or skeletal muscle cells. Each smooth muscle tissue is characterized by a specific pattern of MHC isoform expression that changes during development and disease. This review essentially focuses on SMHC isoforms and their expression in mammals.

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Citations

Sep 23, 1998·The International Journal of Biochemistry & Cell Biology·R B Low, S L White
Nov 18, 2008·Proceedings of the National Academy of Sciences of the United States of America·Mei ChiMuthu Periasamy
Nov 9, 2012·American Journal of Physiology. Cell Physiology·Qian HuangThomas J Eddinger
Aug 26, 2010·Physiological Genomics·Steven A Fisher
Oct 18, 2011·PloS One·Lina A ShehadehRoberto I Vazquez-Padron
Oct 8, 2011·Journal of Smooth Muscle Research = Nihon Heikatsukin Gakkai Kikanshi·Mei ChiMuthu Periasamy
May 24, 2006·The International Journal of Biochemistry & Cell Biology·Robert LowAnne-Marie Lauzon
Sep 1, 2005·Experimental Cell Research·Daniel LarrieuJean-Marie Daniel Lamazière
Sep 21, 2002·Microscopy Research and Technique·Victor Benno Meyer-Rochow, Mar Royuela
Sep 26, 2000·American Journal of Physiology. Cell Physiology·P J GallagherV Lindner
Dec 24, 2003·Laboratory Investigation; a Journal of Technical Methods and Pathology·Alexis DesmoulièreGiulio Gabbiani
Oct 24, 2018·Physiological Reports·Mohamed IssoufJean-Pierre Lavoie

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